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In vivo photoinactivation of Escherichia coli ribonucleoside reductase by near-ultraviolet light

Abstract

Some experimental work is described showing that near-uv irradiation of E.coli cells selectively destroys RDP-reductase (ribonucleoside diphosphate reductase) activity in vivo are providing evidence relating the loss of RDP-reductase to loss of cellular visibility and the inactivity of irrdiated cells to support the replication of DNA phages. The data are consistent with the interpretation that the principal cause in the killing of exponentially growing E.coli cells by near-uv, and the loss of ability of irradiated host cells to support the replication of DNA phages, is the photoinactivation of the RDP-reductase complex.
Authors:
Peters, J [1] 
  1. California Univ., Irvine (USA)
Publication Date:
Jun 09, 1977
Product Type:
Journal Article
Reference Number:
AIX-08-330283; EDB-78-011138
Resource Relation:
Journal Name: Nature (London); (United Kingdom); Journal Volume: 267:5611
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; OXIDOREDUCTASES; BIOLOGICAL RADIATION EFFECTS; ESCHERICHIA COLI; IN VIVO; INACTIVATION; NEAR ULTRAVIOLET RADIATION; RNA-ASE; BACTERIA; BIOLOGICAL EFFECTS; ELECTROMAGNETIC RADIATION; ENZYMES; MICROORGANISMS; PHOSPHOTRANSFERASES; RADIATION EFFECTS; RADIATIONS; TRANSFERASES; ULTRAVIOLET RADIATION; 560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)
OSTI ID:
7083193
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NATUA
Submitting Site:
INIS
Size:
Pages: 546-548
Announcement Date:
Dec 01, 1977

Citation Formats

Peters, J. In vivo photoinactivation of Escherichia coli ribonucleoside reductase by near-ultraviolet light. United Kingdom: N. p., 1977. Web. doi:10.1038/267546a0.
Peters, J. In vivo photoinactivation of Escherichia coli ribonucleoside reductase by near-ultraviolet light. United Kingdom. https://doi.org/10.1038/267546a0
Peters, J. 1977. "In vivo photoinactivation of Escherichia coli ribonucleoside reductase by near-ultraviolet light." United Kingdom. https://doi.org/10.1038/267546a0.
@misc{etde_7083193,
title = {In vivo photoinactivation of Escherichia coli ribonucleoside reductase by near-ultraviolet light}
author = {Peters, J}
abstractNote = {Some experimental work is described showing that near-uv irradiation of E.coli cells selectively destroys RDP-reductase (ribonucleoside diphosphate reductase) activity in vivo are providing evidence relating the loss of RDP-reductase to loss of cellular visibility and the inactivity of irrdiated cells to support the replication of DNA phages. The data are consistent with the interpretation that the principal cause in the killing of exponentially growing E.coli cells by near-uv, and the loss of ability of irradiated host cells to support the replication of DNA phages, is the photoinactivation of the RDP-reductase complex.}
doi = {10.1038/267546a0}
journal = []
volume = {267:5611}
journal type = {AC}
place = {United Kingdom}
year = {1977}
month = {Jun}
}