You need JavaScript to view this

Chromosome abnormalities in atomic bomb survivors

Journal Article:

Abstract

Chromosome abnormalities in bone marrow cells were recognized in 6 cases which consisted of one case of chronic myelogenous leukemia, two cases of acute myelogenous leukemia, one case of sideroblastic anemia, and two cases of myelodysplasis. Frequency of stable type chromosome abnormalities in bone marrow cells was investigated in 45 atomic bomb survivors without hematologic disorders and 15 controls. It was 1.4% (15 cases) in the group exposed to atomic bomb within 1 km from the hypocenter, which was significantly higher as compared with 0.1% (15 cases) in the group exposed to atomic bomb over 2.5 km from the hypocenter and 0.2% in normal controls. Examination of chromosome was also made on 2 of 3 cases which were the seconds born of female with high chromosome abnormality, who was exposed to within 1 km from the hypocenter, and healthy male exposed 3 km from the hypocenter. These two cases showed chromosome of normal male type, and balanced translocation was not recognized. There was not a significant difference in chromosome abnormalities between the seconds of atomic bomb survivors and controls.
Authors:
Tomonaga, Y [1] 
  1. Nagasaki Univ. (Japan). School of Medicine
Publication Date:
Sep 01, 1976
Product Type:
Journal Article
Reference Number:
AIX-08-332462; EDB-78-011225
Resource Relation:
Journal Name: Nagasaki Igakkai Zasshi; (Japan); Journal Volume: 51:3
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; DELAYED RADIATION EFFECTS; BONE MARROW CELLS; CHROMOSOMAL ABERRATIONS; RADIOINDUCTION; ANEMIAS; MYELOID LEUKEMIA; NAGASAKI; ANIMAL CELLS; ASIA; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CONNECTIVE TISSUE CELLS; DISEASES; HEMIC DISEASES; JAPAN; LEUKEMIA; MUTATIONS; NEOPLASMS; RADIATION EFFECTS; SOMATIC CELLS; SYMPTOMS; 560151* - Radiation Effects on Animals- Man
OSTI ID:
7083118
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NAGZA
Submitting Site:
INIS
Size:
Pages: 282-286
Announcement Date:

Journal Article:

Citation Formats

Tomonaga, Y. Chromosome abnormalities in atomic bomb survivors. Japan: N. p., 1976. Web.
Tomonaga, Y. Chromosome abnormalities in atomic bomb survivors. Japan.
Tomonaga, Y. 1976. "Chromosome abnormalities in atomic bomb survivors." Japan.
@misc{etde_7083118,
title = {Chromosome abnormalities in atomic bomb survivors}
author = {Tomonaga, Y}
abstractNote = {Chromosome abnormalities in bone marrow cells were recognized in 6 cases which consisted of one case of chronic myelogenous leukemia, two cases of acute myelogenous leukemia, one case of sideroblastic anemia, and two cases of myelodysplasis. Frequency of stable type chromosome abnormalities in bone marrow cells was investigated in 45 atomic bomb survivors without hematologic disorders and 15 controls. It was 1.4% (15 cases) in the group exposed to atomic bomb within 1 km from the hypocenter, which was significantly higher as compared with 0.1% (15 cases) in the group exposed to atomic bomb over 2.5 km from the hypocenter and 0.2% in normal controls. Examination of chromosome was also made on 2 of 3 cases which were the seconds born of female with high chromosome abnormality, who was exposed to within 1 km from the hypocenter, and healthy male exposed 3 km from the hypocenter. These two cases showed chromosome of normal male type, and balanced translocation was not recognized. There was not a significant difference in chromosome abnormalities between the seconds of atomic bomb survivors and controls.}
journal = {Nagasaki Igakkai Zasshi; (Japan)}
volume = {51:3}
journal type = {AC}
place = {Japan}
year = {1976}
month = {Sep}
}