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Basic theory and methods of dosimetry for use in risk assessment of genotoxic chemicals

Abstract

This project is designed to be theoretical, with limited experimental input. The work then would have to be directed towards an identification of problems, with an emphasis on the potential ability of molecular/biochemical methods to reach a solution, rather than aiming at solutions of the problems. In addition, the work is dependent on experimental work within parallel projects. Initially, projects running at this laboratory were strongly tied up with practical matters, such as the development of monitoring methods for specific exposures, with limited resources for basic research. As sketched in the scientific report below, section 4 the meaningfulness of molecular/biochemical methods and their potential contribution to the problem of dsk estimation has to be seen against a broad overview of this problem and current efforts to solve it. This overview, given as a brief summary in section 3, shows the necessity of combining different fields of research, holding them together by strictly quantitative aspects.
Publication Date:
Jan 01, 1992
Product Type:
Technical Report
Report Number:
DOE/ER/60784-3
Reference Number:
EDB-93-033804
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; CARCINOGENS; RISK ASSESSMENT; MUTAGENS; MATHEMATICAL MODELS; DOSE RATES; DOSE-RESPONSE RELATIONSHIPS; PROGRESS REPORT; DOCUMENT TYPES; 560300* - Chemicals Metabolism & Toxicology
Sponsoring Organizations:
USDOE; USDOE, Washington, DC (United States)
OSTI ID:
7062424
Research Organizations:
Stockholm Univ. (Sweden). Dept. of Radiobiology
Country of Origin:
Sweden
Language:
English
Contract Number:
FG02-89ER60784
Other Identifying Numbers:
Other: ON: DE93007265
Availability:
OSTI; NTIS; GPO Dep.
Submitting Site:
CHO
Size:
Pages: (60 p)
Announcement Date:
Mar 15, 1993

Citation Formats

Ehrenberg, L, and Granath, F. Basic theory and methods of dosimetry for use in risk assessment of genotoxic chemicals. Sweden: N. p., 1992. Web.
Ehrenberg, L, & Granath, F. Basic theory and methods of dosimetry for use in risk assessment of genotoxic chemicals. Sweden.
Ehrenberg, L, and Granath, F. 1992. "Basic theory and methods of dosimetry for use in risk assessment of genotoxic chemicals." Sweden.
@misc{etde_7062424,
title = {Basic theory and methods of dosimetry for use in risk assessment of genotoxic chemicals}
author = {Ehrenberg, L, and Granath, F}
abstractNote = {This project is designed to be theoretical, with limited experimental input. The work then would have to be directed towards an identification of problems, with an emphasis on the potential ability of molecular/biochemical methods to reach a solution, rather than aiming at solutions of the problems. In addition, the work is dependent on experimental work within parallel projects. Initially, projects running at this laboratory were strongly tied up with practical matters, such as the development of monitoring methods for specific exposures, with limited resources for basic research. As sketched in the scientific report below, section 4 the meaningfulness of molecular/biochemical methods and their potential contribution to the problem of dsk estimation has to be seen against a broad overview of this problem and current efforts to solve it. This overview, given as a brief summary in section 3, shows the necessity of combining different fields of research, holding them together by strictly quantitative aspects.}
place = {Sweden}
year = {1992}
month = {Jan}
}