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Metabolism features in the active rheumatoid disease

Journal Article:

Abstract

The /sup 131/I-labelled albumin metabolism was studied in fourteen female patients with rheumatoid arthritis. The half-life of distribution was increased while the turnover half-life and turnover rate was within normal limits. These results led to assume that synthesis and catabolism may not change this disease, not being the responsible mechanism of hypoalbuminemia. Hypoalbuminemia would appear as compensatory mechanism in view of other protein alterations, as hypergammaglobulinemia, without changes of stabilizing and metabolic properties of albumin, perhaps due to albumin molecular alterations.
Authors:
Cossermelli, W; Carvalho, N; Papaleo Netto, M [1] 
  1. Sao Paulo Univ. (Brazil). Centro de Medicina Nuclear
Publication Date:
Feb 01, 1974
Product Type:
Journal Article
Reference Number:
AIX-09-382711; EDB-78-098654
Resource Relation:
Journal Name: Rev. Assoc. Med. Bras.; (Brazil); Journal Volume: 20:2
Subject:
59 BASIC BIOLOGICAL SCIENCES; ALBUMINS; METABOLISM; RHEUMATIC DISEASES; CATABOLISM; DECOMPOSITION; GLOBULINS-GAMMA; INFLAMMATION; IODINE 131; LUGOL; MOLECULAR STRUCTURE; PATIENTS; STATISTICS; SYNTHESIS; TRACER TECHNIQUES; UPTAKE; WOMEN; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHEMICAL REACTIONS; DAYS LIVING RADIOISOTOPES; DISEASES; FEMALES; GLOBULINS; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MAN; MATHEMATICS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PATHOLOGICAL CHANGES; PRIMATES; PROTEINS; RADIOISOTOPES; SKELETAL DISEASES; VERTEBRATES; 550901* - Pathology- Tracer Techniques
OSTI ID:
7057323
Country of Origin:
Brazil
Language:
Portuguese
Other Identifying Numbers:
Journal ID: CODEN: RMDBA
Submitting Site:
INIS
Size:
Pages: 67-69
Announcement Date:
Jun 01, 1978

Journal Article:

Citation Formats

Cossermelli, W, Carvalho, N, and Papaleo Netto, M. Metabolism features in the active rheumatoid disease. Brazil: N. p., 1974. Web.
Cossermelli, W, Carvalho, N, & Papaleo Netto, M. Metabolism features in the active rheumatoid disease. Brazil.
Cossermelli, W, Carvalho, N, and Papaleo Netto, M. 1974. "Metabolism features in the active rheumatoid disease." Brazil.
@misc{etde_7057323,
title = {Metabolism features in the active rheumatoid disease}
author = {Cossermelli, W, Carvalho, N, and Papaleo Netto, M}
abstractNote = {The /sup 131/I-labelled albumin metabolism was studied in fourteen female patients with rheumatoid arthritis. The half-life of distribution was increased while the turnover half-life and turnover rate was within normal limits. These results led to assume that synthesis and catabolism may not change this disease, not being the responsible mechanism of hypoalbuminemia. Hypoalbuminemia would appear as compensatory mechanism in view of other protein alterations, as hypergammaglobulinemia, without changes of stabilizing and metabolic properties of albumin, perhaps due to albumin molecular alterations.}
journal = {Rev. Assoc. Med. Bras.; (Brazil)}
volume = {20:2}
journal type = {AC}
place = {Brazil}
year = {1974}
month = {Feb}
}