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Single photon emission computed tomography study of human pulmonary perfusion: preliminary findings

Journal Article:

Abstract

Single photon emission computed tomography (SPECT) was performed with /sup 99/Tcsup(m)-albumin macroaggregates to study human pulmonary perfusion in healthy subjects and patients with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and lung neoplasms. The reconstructed SPECT data was displayed in coronal, transverse, sagittal plane sections and compared to conventional perfusion scans. The SPECT data gave more complicated anatomical information about the extent of damage and morphology of the pulmonary vascular bed. In healthy subjects and COPD patients, qualitative and quantitative assessment of pulmonary perfusion could be obtained from serial SPECT scans with respect to distribution and relative concentration of the injected radiopharmaceutical. Furthermore, SPECT of pulmonary perfusion has been useful in detecting the extent of damage to the pulmonary circulation. This is useful for the preoperative evaluation and staging of lung cancer.
Authors:
Carratu, L; Sofia, M; [1]  Salvatore, M; Muto, P; Ariemma, G; [2]  Lopez-Majano, V [3] 
  1. Naples Univ. (Italy). Facolta di Medicina e Chirurgia
  2. Istituto Nazionale per la Prevenzione, Lo Studio e La Cura dei Tumori Fondazione Pascale, Naples (Italy)
  3. Cook County Hospital, Chicago, IL (USA). Nuclear Medicine Div.
Publication Date:
Feb 01, 1984
Product Type:
Journal Article
Reference Number:
AIX-15-038917; EDB-84-111431
Resource Relation:
Journal Name: Nucl. Med. Commun.; (United Kingdom); Journal Volume: 5:2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ALBUMINS; DIAGNOSTIC USES; LUNGS; SCINTISCANNING; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; RESPIRATORY SYSTEM DISEASES; DIAGNOSIS; TECHNETIUM 99; BLOOD CIRCULATION; BLOOD FLOW; CARCINOMAS; COMPARATIVE EVALUATIONS; MAN; REFERENCE MAN; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; EMISSION COMPUTED TOMOGRAPHY; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; PRIMATES; PROTEINS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; TECHNETIUM ISOTOPES; TOMOGRAPHY; USES; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7055974
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NMCOD
Submitting Site:
HEDB
Size:
Pages: 91-99
Announcement Date:

Journal Article:

Citation Formats

Carratu, L, Sofia, M, Salvatore, M, Muto, P, Ariemma, G, and Lopez-Majano, V. Single photon emission computed tomography study of human pulmonary perfusion: preliminary findings. United Kingdom: N. p., 1984. Web.
Carratu, L, Sofia, M, Salvatore, M, Muto, P, Ariemma, G, & Lopez-Majano, V. Single photon emission computed tomography study of human pulmonary perfusion: preliminary findings. United Kingdom.
Carratu, L, Sofia, M, Salvatore, M, Muto, P, Ariemma, G, and Lopez-Majano, V. 1984. "Single photon emission computed tomography study of human pulmonary perfusion: preliminary findings." United Kingdom.
@misc{etde_7055974,
title = {Single photon emission computed tomography study of human pulmonary perfusion: preliminary findings}
author = {Carratu, L, Sofia, M, Salvatore, M, Muto, P, Ariemma, G, and Lopez-Majano, V}
abstractNote = {Single photon emission computed tomography (SPECT) was performed with /sup 99/Tcsup(m)-albumin macroaggregates to study human pulmonary perfusion in healthy subjects and patients with respiratory diseases such as chronic obstructive pulmonary disease (COPD) and lung neoplasms. The reconstructed SPECT data was displayed in coronal, transverse, sagittal plane sections and compared to conventional perfusion scans. The SPECT data gave more complicated anatomical information about the extent of damage and morphology of the pulmonary vascular bed. In healthy subjects and COPD patients, qualitative and quantitative assessment of pulmonary perfusion could be obtained from serial SPECT scans with respect to distribution and relative concentration of the injected radiopharmaceutical. Furthermore, SPECT of pulmonary perfusion has been useful in detecting the extent of damage to the pulmonary circulation. This is useful for the preoperative evaluation and staging of lung cancer.}
journal = {Nucl. Med. Commun.; (United Kingdom)}
volume = {5:2}
journal type = {AC}
place = {United Kingdom}
year = {1984}
month = {Feb}
}