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Effect of insulin phase state in water on its radiation stability

Abstract

Radiation stability of the aqueous solution and the insulin suspension is investigated. The degree of radiation transformations is determined by means of chromatography on paper and with the method of cramp reaction in mice. ..gamma..-irradiation is carried out at room temperature, at dose rate of 0.75 M rad/h. The data obtained prove the earlier suggested hypothesis of a phase division of a biologically active compound, personally medicinal substance and water (for example, in the case of which permits to prolong the preservation of medicine in the case of irradiation.
Authors:
Publication Date:
Jan 01, 1980
Product Type:
Journal Article
Reference Number:
AIX-12-580817; EDB-81-027277
Resource Relation:
Journal Name: Dokl. Akad. Nauk SSSR; (USSR); Journal Volume: 251:5
Subject:
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; INSULIN; CHEMICAL RADIATION EFFECTS; AQUEOUS SOLUTIONS; DOSE RATES; GAMMA RADIATION; MEDIUM TEMPERATURE; SUSPENSIONS; CHEMISTRY; DISPERSIONS; ELECTROMAGNETIC RADIATION; HORMONES; IONIZING RADIATIONS; MIXTURES; PEPTIDE HORMONES; RADIATION CHEMISTRY; RADIATION EFFECTS; RADIATIONS; SOLUTIONS; 400600* - Radiation Chemistry
OSTI ID:
7051162
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: DANKA
Submitting Site:
INIS
Size:
Pages: 1178-1182
Announcement Date:
Feb 01, 1981

Citation Formats

Soboleva, N N, Ivanova, A I, Tal'roze, V L, Trofimov, V I, Fedotov, V P, AN SSSR, Moscow. Inst. Khimicheskoj Fiziki, and Akademiya Meditsinskikh Nauk SSSR, Moscow. Inst. Ehksperimental'noj Ehndokrinologii i Khimii Gormonov). Effect of insulin phase state in water on its radiation stability. USSR: N. p., 1980. Web.
Soboleva, N N, Ivanova, A I, Tal'roze, V L, Trofimov, V I, Fedotov, V P, AN SSSR, Moscow. Inst. Khimicheskoj Fiziki, & Akademiya Meditsinskikh Nauk SSSR, Moscow. Inst. Ehksperimental'noj Ehndokrinologii i Khimii Gormonov). Effect of insulin phase state in water on its radiation stability. USSR.
Soboleva, N N, Ivanova, A I, Tal'roze, V L, Trofimov, V I, Fedotov, V P, AN SSSR, Moscow. Inst. Khimicheskoj Fiziki, and Akademiya Meditsinskikh Nauk SSSR, Moscow. Inst. Ehksperimental'noj Ehndokrinologii i Khimii Gormonov). 1980. "Effect of insulin phase state in water on its radiation stability." USSR.
@misc{etde_7051162,
title = {Effect of insulin phase state in water on its radiation stability}
author = {Soboleva, N N, Ivanova, A I, Tal'roze, V L, Trofimov, V I, Fedotov, V P, AN SSSR, Moscow. Inst. Khimicheskoj Fiziki, and Akademiya Meditsinskikh Nauk SSSR, Moscow. Inst. Ehksperimental'noj Ehndokrinologii i Khimii Gormonov)}
abstractNote = {Radiation stability of the aqueous solution and the insulin suspension is investigated. The degree of radiation transformations is determined by means of chromatography on paper and with the method of cramp reaction in mice. ..gamma..-irradiation is carried out at room temperature, at dose rate of 0.75 M rad/h. The data obtained prove the earlier suggested hypothesis of a phase division of a biologically active compound, personally medicinal substance and water (for example, in the case of which permits to prolong the preservation of medicine in the case of irradiation.}
journal = []
volume = {251:5}
journal type = {AC}
place = {USSR}
year = {1980}
month = {Jan}
}