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Positron emission tomography. Positronemisionstomografi

Journal Article:

Abstract

Positron emission tomography (PET) is a method for quantitative imaging of regional physiological and biochemical parameters. Positron emitting radioactive isotopes can be produced by a cyclotron, eg. the biologically important carbon ([sup 11]C), oxygen ([sup 15]O), and nitrogen ([sup 13]N) elements. With the tomographic principles of the PET scanner the quantitative distribution of the administered isotopes can be determined and images can be provided as well as dynamic information on blood flow, metabolism and receptor function. In neurology PET has been used for investigations on numerous physiological processes in the brain: circulation, metabolism and receptor studies. In Parkinson's disease PET studies have been able to localize the pathology specifically, and in early stroke PET technique can outline focal areas with living but non-functioning cells, and this could make it possible to intervene in this early state. With positron emission tomography a quantitative evaluation of myocardial blood flow, glucose and fatty acid metabolism can be made as well as combined assessments of blood flow and metabolism. Combined studies of blood flow and metabolism can determine whether myocardial segments with abnormal motility consist of necrotic or viable tissue, thereby delineating effects of revascularisation. In the future it will probably be possible to  More>>
Publication Date:
Oct 01, 1994
Product Type:
Journal Article
Reference Number:
AIX-26-008258; EDB-95-010083
Resource Relation:
Journal Name: Ugeskrift for Laeger; (Denmark); Journal Volume: 156:43
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; POSITRON COMPUTED TOMOGRAPHY; ISOTOPE PRODUCTION; RADIOISOTOPE SCANNING; CARBON 11; CYCLOTRONS; IMAGE SCANNERS; NITROGEN 13; OXYGEN 15; PATIENTS; ACCELERATORS; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; CARBON ISOTOPES; COMPUTERIZED TOMOGRAPHY; COUNTING TECHNIQUES; CYCLIC ACCELERATORS; DIAGNOSTIC TECHNIQUES; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; EVEN-ODD NUCLEI; ISOTOPES; LIGHT NUCLEI; MINUTES LIVING RADIOISOTOPES; NITROGEN ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; OXYGEN ISOTOPES; RADIOISOTOPES; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
7029127
Country of Origin:
Denmark
Language:
Danish
Other Identifying Numbers:
Journal ID: ISSN 0041-5782; CODEN: UGLAAD
Submitting Site:
DKN
Size:
Pages: 6341-6347
Announcement Date:

Journal Article:

Citation Formats

Bolwig, T G, Haunsoe, S, Dahlgaard Hove, J, Hesse, B, Hoejgard, L, Jensen, M, Paulson, O B, Hastrup Svendsen, J, and Soelvsten Soerensen, S. Positron emission tomography. Positronemisionstomografi. Denmark: N. p., 1994. Web.
Bolwig, T G, Haunsoe, S, Dahlgaard Hove, J, Hesse, B, Hoejgard, L, Jensen, M, Paulson, O B, Hastrup Svendsen, J, & Soelvsten Soerensen, S. Positron emission tomography. Positronemisionstomografi. Denmark.
Bolwig, T G, Haunsoe, S, Dahlgaard Hove, J, Hesse, B, Hoejgard, L, Jensen, M, Paulson, O B, Hastrup Svendsen, J, and Soelvsten Soerensen, S. 1994. "Positron emission tomography. Positronemisionstomografi." Denmark.
@misc{etde_7029127,
title = {Positron emission tomography. Positronemisionstomografi}
author = {Bolwig, T G, Haunsoe, S, Dahlgaard Hove, J, Hesse, B, Hoejgard, L, Jensen, M, Paulson, O B, Hastrup Svendsen, J, and Soelvsten Soerensen, S}
abstractNote = {Positron emission tomography (PET) is a method for quantitative imaging of regional physiological and biochemical parameters. Positron emitting radioactive isotopes can be produced by a cyclotron, eg. the biologically important carbon ([sup 11]C), oxygen ([sup 15]O), and nitrogen ([sup 13]N) elements. With the tomographic principles of the PET scanner the quantitative distribution of the administered isotopes can be determined and images can be provided as well as dynamic information on blood flow, metabolism and receptor function. In neurology PET has been used for investigations on numerous physiological processes in the brain: circulation, metabolism and receptor studies. In Parkinson's disease PET studies have been able to localize the pathology specifically, and in early stroke PET technique can outline focal areas with living but non-functioning cells, and this could make it possible to intervene in this early state. With positron emission tomography a quantitative evaluation of myocardial blood flow, glucose and fatty acid metabolism can be made as well as combined assessments of blood flow and metabolism. Combined studies of blood flow and metabolism can determine whether myocardial segments with abnormal motility consist of necrotic or viable tissue, thereby delineating effects of revascularisation. In the future it will probably be possible to characterize the myocardial receptor status in different cardiac diseases. The PET technique is used in oncology for clinical as well as more basic research on tumor perfusion and metabolism. Further, tumor uptake of positron labelled cytotoxic drugs might predict the clinical benefit of treatment. (au) (19 refs.).}
journal = {Ugeskrift for Laeger; (Denmark)}
volume = {156:43}
journal type = {AC}
place = {Denmark}
year = {1994}
month = {Oct}
}