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Central nervous system reactions to cervical myelography

Journal Article:

Abstract

In a double blind prospective study of side effects to cervical myelography 38 patients were evaluated with neurologic examination, electroencephalography (EEG), brainstem evoked response (BER), somatosensory evoked responses (SSER), and continuous reaction times prior to and at 6 h and 24 h after myelography with either metrizamide or iohexol. A difference in the incidence of side effects (for example headache, dizziness, nausea, and neck pain) to the two different contrast media indicated that the inconveniences related to myelography were not only due to the spinal puncture. A contrast medium effect on the central nervous system varying from one agent to another was present. A high frequency of EEG deteriorations among patients with adverse clinical reactions and on only discrete affection upon BER indicated the reaction to be located to the cerebral cortex. Weakened tendon reflexes and reduced strength in the upper extremities were probably caused by blockade in the motor roots as SSER were normal indicating no affection of the sensory pathways. This hypothesis is in agreement with the fact the patients were in the prone position in the first phase of the investigation causing the highest concentration of contrast medium around the motor roots and the anterior part of  More>>
Authors:
Vestergaard, A; Dons, K; Eskesen, V; Kruse-Larsen, C; Blatt Lyon, B; Arlien Soeborg, P; Jensen, N O; Praestholm, J [1] 
  1. Hvidovre Hospital (Denmark). Depts. of Diagnostic Radiology, Neurosurgery, Neurology, and Clinical Neurophysiology
Publication Date:
Sep 01, 1991
Product Type:
Journal Article
Reference Number:
AIX-23-075275; EDB-92-152352
Resource Relation:
Journal Name: Acta Radiologica (1987); (Sweden); Journal Volume: 32:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CONTRAST MEDIA; SIDE EFFECTS; SPINAL CORD; BIOMEDICAL RADIOGRAPHY; BRAIN; IOHEXOL; METRIZAMIDE; NECK; PATIENTS; PHYSIOLOGY; TOXICITY; X-RAY RADIOGRAPHY; AMIDES; BODY; BODY AREAS; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; INDUSTRIAL RADIOGRAPHY; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; RADIOLOGY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
7028622
Country of Origin:
Sweden
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0284-1851; CODEN: ACRAE
Submitting Site:
SWDN
Size:
Pages: 411-414
Announcement Date:

Journal Article:

Citation Formats

Vestergaard, A, Dons, K, Eskesen, V, Kruse-Larsen, C, Blatt Lyon, B, Arlien Soeborg, P, Jensen, N O, and Praestholm, J. Central nervous system reactions to cervical myelography. Sweden: N. p., 1991. Web.
Vestergaard, A, Dons, K, Eskesen, V, Kruse-Larsen, C, Blatt Lyon, B, Arlien Soeborg, P, Jensen, N O, & Praestholm, J. Central nervous system reactions to cervical myelography. Sweden.
Vestergaard, A, Dons, K, Eskesen, V, Kruse-Larsen, C, Blatt Lyon, B, Arlien Soeborg, P, Jensen, N O, and Praestholm, J. 1991. "Central nervous system reactions to cervical myelography." Sweden.
@misc{etde_7028622,
title = {Central nervous system reactions to cervical myelography}
author = {Vestergaard, A, Dons, K, Eskesen, V, Kruse-Larsen, C, Blatt Lyon, B, Arlien Soeborg, P, Jensen, N O, and Praestholm, J}
abstractNote = {In a double blind prospective study of side effects to cervical myelography 38 patients were evaluated with neurologic examination, electroencephalography (EEG), brainstem evoked response (BER), somatosensory evoked responses (SSER), and continuous reaction times prior to and at 6 h and 24 h after myelography with either metrizamide or iohexol. A difference in the incidence of side effects (for example headache, dizziness, nausea, and neck pain) to the two different contrast media indicated that the inconveniences related to myelography were not only due to the spinal puncture. A contrast medium effect on the central nervous system varying from one agent to another was present. A high frequency of EEG deteriorations among patients with adverse clinical reactions and on only discrete affection upon BER indicated the reaction to be located to the cerebral cortex. Weakened tendon reflexes and reduced strength in the upper extremities were probably caused by blockade in the motor roots as SSER were normal indicating no affection of the sensory pathways. This hypothesis is in agreement with the fact the patients were in the prone position in the first phase of the investigation causing the highest concentration of contrast medium around the motor roots and the anterior part of the spinal cord. Difference in metabolic effect may explain differences in side effects of metrizamide and iohexol. (orig.).}
journal = {Acta Radiologica (1987); (Sweden)}
volume = {32:5}
journal type = {AC}
place = {Sweden}
year = {1991}
month = {Sep}
}