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Effect of radiation therapy against intracranial hemangiopericytoma

Journal Article:

Abstract

Seven cases of intracranial hemangiopericytoma were studied retrospectively to investigate the efficacy of radiation therapy. Tumor response evaluated by computed tomography and magnetic resonance imaging was obvious after 20-30 Gy irradiation. The total reduction rate was 80-90% and continued as long as 5-7 months after treatment. In five patients receiving radiation therapy before radical removal, the tumors were easily removed without massive hemorrhage. Histological inspection of specimens after irradiation showed a significant disappearance of tumor cells. Pyknosis frequently occurred in endothelial cells, and proliferating vessels with hyalinoid degeneration were also seen. Reticulin fibers between tumor cells were fewer, split, or absent. Preoperative radiation therapy is useful in the treatment of hemangiopericytoma involving considerable surgical risk. Postoperative radiation therapy should be given even if removal is complete. (author).
Authors:
Publication Date:
Jun 01, 1992
Product Type:
Journal Article
Reference Number:
JPN-92-008436; EDB-92-152450
Resource Relation:
Journal Name: Neurologia Medico-Chirurgica; (Japan); Journal Volume: 32:6
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; RADIOTHERAPY; ANGIOMAS; CAT SCANNING; HEMORRHAGE; MENINGES; NEOPLASMS; NMR IMAGING; PATIENTS; TIME DEPENDENCE; TUMOR CELLS; ANIMAL CELLS; BODY; CARCINOMAS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; MEDICINE; MEMBRANES; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIOLOGY; SYMPTOMS; THERAPY; TOMOGRAPHY; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
7028491
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0387-2572; CODEN: NMCHB
Submitting Site:
JPN
Size:
Pages: 328-332
Announcement Date:

Journal Article:

Citation Formats

Uemura, Shozaburo, Kuratsu, Jun-ichi, Hamada, Jun-ichiro, Yoshioka, Susumu, Kochi, Masato, Ushio, Yukitaka, Nakahara, Tadashi, and Kishida, Katsuaki. Effect of radiation therapy against intracranial hemangiopericytoma. Japan: N. p., 1992. Web.
Uemura, Shozaburo, Kuratsu, Jun-ichi, Hamada, Jun-ichiro, Yoshioka, Susumu, Kochi, Masato, Ushio, Yukitaka, Nakahara, Tadashi, & Kishida, Katsuaki. Effect of radiation therapy against intracranial hemangiopericytoma. Japan.
Uemura, Shozaburo, Kuratsu, Jun-ichi, Hamada, Jun-ichiro, Yoshioka, Susumu, Kochi, Masato, Ushio, Yukitaka, Nakahara, Tadashi, and Kishida, Katsuaki. 1992. "Effect of radiation therapy against intracranial hemangiopericytoma." Japan.
@misc{etde_7028491,
title = {Effect of radiation therapy against intracranial hemangiopericytoma}
author = {Uemura, Shozaburo, Kuratsu, Jun-ichi, Hamada, Jun-ichiro, Yoshioka, Susumu, Kochi, Masato, Ushio, Yukitaka, Nakahara, Tadashi, and Kishida, Katsuaki}
abstractNote = {Seven cases of intracranial hemangiopericytoma were studied retrospectively to investigate the efficacy of radiation therapy. Tumor response evaluated by computed tomography and magnetic resonance imaging was obvious after 20-30 Gy irradiation. The total reduction rate was 80-90% and continued as long as 5-7 months after treatment. In five patients receiving radiation therapy before radical removal, the tumors were easily removed without massive hemorrhage. Histological inspection of specimens after irradiation showed a significant disappearance of tumor cells. Pyknosis frequently occurred in endothelial cells, and proliferating vessels with hyalinoid degeneration were also seen. Reticulin fibers between tumor cells were fewer, split, or absent. Preoperative radiation therapy is useful in the treatment of hemangiopericytoma involving considerable surgical risk. Postoperative radiation therapy should be given even if removal is complete. (author).}
journal = {Neurologia Medico-Chirurgica; (Japan)}
volume = {32:6}
journal type = {AC}
place = {Japan}
year = {1992}
month = {Jun}
}