Abstract
[[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a] [1,4]benzodiazepine 3-carboxylate ([[sup 123]I]3), a high affinity and selective radioligand for the diazepam insensitive (DI) benzodiazepine receptor was synthesized in 2 steps from tert-butyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaz epine 3-carboxylate. (Author).
He, Xiaoshu;
Matecka, Dorota;
Gu, Ziqiang;
Rice, K C;
Costa, B.R. de;
[1]
Lee, K S;
[2]
Wong, Garry;
Skolnick, Phil
[3]
- National Inst. of Diabetes and Digestive and Kidney Diseases, Bethesda, MD (United States)
- National Inst. of Mental Health, Washington, DC (United States)
- National Inst. of Diabetes and Digestive and Kidney Diseases, Bethesda, MD (United States). Lab. of Neuroscience
Citation Formats
He, Xiaoshu, Matecka, Dorota, Gu, Ziqiang, Rice, K C, Costa, B.R. de, Lee, K S, Wong, Garry, and Skolnick, Phil.
Synthesis of [[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaze pine 3-carboxylate, a potential SPECT imaging agent for diazepam-intensive (DI) benzodiazepine receptors.
United Kingdom: N. p.,
1994.
Web.
He, Xiaoshu, Matecka, Dorota, Gu, Ziqiang, Rice, K C, Costa, B.R. de, Lee, K S, Wong, Garry, & Skolnick, Phil.
Synthesis of [[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaze pine 3-carboxylate, a potential SPECT imaging agent for diazepam-intensive (DI) benzodiazepine receptors.
United Kingdom.
He, Xiaoshu, Matecka, Dorota, Gu, Ziqiang, Rice, K C, Costa, B.R. de, Lee, K S, Wong, Garry, and Skolnick, Phil.
1994.
"Synthesis of [[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaze pine 3-carboxylate, a potential SPECT imaging agent for diazepam-intensive (DI) benzodiazepine receptors."
United Kingdom.
@misc{etde_7003821,
title = {Synthesis of [[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaze pine 3-carboxylate, a potential SPECT imaging agent for diazepam-intensive (DI) benzodiazepine receptors}
author = {He, Xiaoshu, Matecka, Dorota, Gu, Ziqiang, Rice, K C, Costa, B.R. de, Lee, K S, Wong, Garry, and Skolnick, Phil}
abstractNote = {[[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a] [1,4]benzodiazepine 3-carboxylate ([[sup 123]I]3), a high affinity and selective radioligand for the diazepam insensitive (DI) benzodiazepine receptor was synthesized in 2 steps from tert-butyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaz epine 3-carboxylate. (Author).}
journal = []
volume = {34:1}
journal type = {AC}
place = {United Kingdom}
year = {1994}
month = {Jan}
}
title = {Synthesis of [[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaze pine 3-carboxylate, a potential SPECT imaging agent for diazepam-intensive (DI) benzodiazepine receptors}
author = {He, Xiaoshu, Matecka, Dorota, Gu, Ziqiang, Rice, K C, Costa, B.R. de, Lee, K S, Wong, Garry, and Skolnick, Phil}
abstractNote = {[[sup 123]I]tert-Butyl 8-iodo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo [1,5-a] [1,4]benzodiazepine 3-carboxylate ([[sup 123]I]3), a high affinity and selective radioligand for the diazepam insensitive (DI) benzodiazepine receptor was synthesized in 2 steps from tert-butyl 8-bromo-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]benzodiaz epine 3-carboxylate. (Author).}
journal = []
volume = {34:1}
journal type = {AC}
place = {United Kingdom}
year = {1994}
month = {Jan}
}