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Atypical case of Reye's syndrome. Usefulness of CT for diagnosis and follow-up study

Journal Article:

Abstract

An atypical case of Reye's syndrome was reported with emphasis on usefulness of CT for the diagnosis and follow-up study of this disease. The patient was a 13-month-old girl who had been transferred to our hospital because of status epilepticus, a comatous state and a high temperature. She was diagnosed as having Reye's syndrome according to data of liver function tests, findings in CSF and body CT which revealed swelling of the liver with diminished attenuation value suggesting fatty infiltration. However, there were atypical features in this patient: epileptic seizures since age 5 months, no vomiting at the time of onset and no evidence of brain swelling on CT in acute phase. She was discharged 2 months later with impaired neuropsychological functions of marked degree. When she was 2 year-old, she again went into status epilepticus, was comatous and had a high temperature. She was dead when she arrived at emergency room of our hospital. Autopsy findings revealed features of Reye's syndrome as follows: abundant accumulation of small fat droplets without nuclear displacement in the liver, fatty infiltration in the kidney and myocardium, and mild swelling in the cerebral cortex with marked ventricular dilatation. The possibility of recurrence of Reye's  More>>
Authors:
Publication Date:
Dec 01, 1982
Product Type:
Journal Article
Reference Number:
AIX-15-033465; EDB-84-095089
Resource Relation:
Journal Name: Igaku Kiyo Fukuoka Daigaku; (Japan); Journal Volume: 9:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; CAT SCANNING; INFANTS; AUTOPSY; DIAGNOSIS; LIVER; NERVOUS SYSTEM DISEASES; PATHOLOGY; PATIENTS; AGE GROUPS; BODY; CENTRAL NERVOUS SYSTEM; CHILDREN; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; NERVOUS SYSTEM; ORGANS; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6970027
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: IGKID
Submitting Site:
HEDB
Size:
Pages: 393-400
Announcement Date:

Journal Article:

Citation Formats

Maehara, Fumiaki, Goto, Katsuya, Okudera, Toshio, Mitsudome, Akihisa, Hara, Kunio, and Shiraishi, Masayuki. Atypical case of Reye's syndrome. Usefulness of CT for diagnosis and follow-up study. Japan: N. p., 1982. Web.
Maehara, Fumiaki, Goto, Katsuya, Okudera, Toshio, Mitsudome, Akihisa, Hara, Kunio, & Shiraishi, Masayuki. Atypical case of Reye's syndrome. Usefulness of CT for diagnosis and follow-up study. Japan.
Maehara, Fumiaki, Goto, Katsuya, Okudera, Toshio, Mitsudome, Akihisa, Hara, Kunio, and Shiraishi, Masayuki. 1982. "Atypical case of Reye's syndrome. Usefulness of CT for diagnosis and follow-up study." Japan.
@misc{etde_6970027,
title = {Atypical case of Reye's syndrome. Usefulness of CT for diagnosis and follow-up study}
author = {Maehara, Fumiaki, Goto, Katsuya, Okudera, Toshio, Mitsudome, Akihisa, Hara, Kunio, and Shiraishi, Masayuki}
abstractNote = {An atypical case of Reye's syndrome was reported with emphasis on usefulness of CT for the diagnosis and follow-up study of this disease. The patient was a 13-month-old girl who had been transferred to our hospital because of status epilepticus, a comatous state and a high temperature. She was diagnosed as having Reye's syndrome according to data of liver function tests, findings in CSF and body CT which revealed swelling of the liver with diminished attenuation value suggesting fatty infiltration. However, there were atypical features in this patient: epileptic seizures since age 5 months, no vomiting at the time of onset and no evidence of brain swelling on CT in acute phase. She was discharged 2 months later with impaired neuropsychological functions of marked degree. When she was 2 year-old, she again went into status epilepticus, was comatous and had a high temperature. She was dead when she arrived at emergency room of our hospital. Autopsy findings revealed features of Reye's syndrome as follows: abundant accumulation of small fat droplets without nuclear displacement in the liver, fatty infiltration in the kidney and myocardium, and mild swelling in the cerebral cortex with marked ventricular dilatation. The possibility of recurrence of Reye's syndrome was discussed based on the clinical and autopsy findings. The value of CT in the diagnosis and the follow-up study of this disease was emphasized.}
journal = {Igaku Kiyo Fukuoka Daigaku; (Japan)}
volume = {9:4}
journal type = {AC}
place = {Japan}
year = {1982}
month = {Dec}
}