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Transplantation of autologous bone marrow in three patients with acute myelogenous leukaemia during the first remission

Abstract

A report is presented on the first results of transplantation of autologous bone marrow in 3 adult patients with acute myelogenous leukaemia. The treatment consisted of intensive chemotherapy and whole-body irradiation and was followed by transplantation of a limited number of non-purified bone-marrow cells that had previously been collected from the patient. In all three patients, transplantation was followed by a stable remission. One patient had a fatal recurrence after a total period of 21 months of remission. In 2 patients, the remissions continue. The clinical significance of these findings is discussed.
Authors:
Loewenberg, B; Sizoo, W; Sintnicolaas, K; Hendriks, W D.H.; Poel, J van der; [1]  Abels, J; Dzoljic, G; [2]  Bekkum, D.W. van; Wagemaker, G [3] 
  1. Rotterdams Radio Therapeutisch Inst. (Netherlands)
  2. Akademisch Ziekenhuis Rotterdam-Dijkzigt (Netherlands)
  3. Gezondheidsorganisatie TNO, Rijswijk (Netherlands). Radiobiologisch Inst. TNO
Publication Date:
Jul 23, 1983
Product Type:
Journal Article
Reference Number:
AIX-15-025076; EDB-84-086574
Resource Relation:
Journal Name: Ned. Tijdschr. Geneesk.; (Netherlands); Journal Volume: 127:30
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; MYELOID LEUKEMIA; RADIOTHERAPY; BIOLOGICAL RADIATION EFFECTS; BONE MARROW; CHEMOTHERAPY; GRAFTS; RADIATION DOSES; SYNERGISM; WHOLE-BODY IRRADIATION; ANIMAL TISSUES; BIOLOGICAL EFFECTS; BODY; DISEASES; DOSES; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; HEMIC DISEASES; IRRADIATION; LEUKEMIA; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANS; RADIATION EFFECTS; RADIOLOGY; THERAPY; TISSUES; TRANSPLANTS; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
6964630
Country of Origin:
Netherlands
Language:
Dutch
Other Identifying Numbers:
Journal ID: CODEN: NIGEA
Submitting Site:
HEDB
Size:
Pages: 1329-1332
Announcement Date:
Mar 01, 1984

Citation Formats

Loewenberg, B, Sizoo, W, Sintnicolaas, K, Hendriks, W D.H., Poel, J van der, Abels, J, Dzoljic, G, Bekkum, D.W. van, and Wagemaker, G. Transplantation of autologous bone marrow in three patients with acute myelogenous leukaemia during the first remission. Netherlands: N. p., 1983. Web.
Loewenberg, B, Sizoo, W, Sintnicolaas, K, Hendriks, W D.H., Poel, J van der, Abels, J, Dzoljic, G, Bekkum, D.W. van, & Wagemaker, G. Transplantation of autologous bone marrow in three patients with acute myelogenous leukaemia during the first remission. Netherlands.
Loewenberg, B, Sizoo, W, Sintnicolaas, K, Hendriks, W D.H., Poel, J van der, Abels, J, Dzoljic, G, Bekkum, D.W. van, and Wagemaker, G. 1983. "Transplantation of autologous bone marrow in three patients with acute myelogenous leukaemia during the first remission." Netherlands.
@misc{etde_6964630,
title = {Transplantation of autologous bone marrow in three patients with acute myelogenous leukaemia during the first remission}
author = {Loewenberg, B, Sizoo, W, Sintnicolaas, K, Hendriks, W D.H., Poel, J van der, Abels, J, Dzoljic, G, Bekkum, D.W. van, and Wagemaker, G}
abstractNote = {A report is presented on the first results of transplantation of autologous bone marrow in 3 adult patients with acute myelogenous leukaemia. The treatment consisted of intensive chemotherapy and whole-body irradiation and was followed by transplantation of a limited number of non-purified bone-marrow cells that had previously been collected from the patient. In all three patients, transplantation was followed by a stable remission. One patient had a fatal recurrence after a total period of 21 months of remission. In 2 patients, the remissions continue. The clinical significance of these findings is discussed.}
journal = []
volume = {127:30}
journal type = {AC}
place = {Netherlands}
year = {1983}
month = {Jul}
}