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Aseptic necrosis of the femoral head following treatment of malignant lymphomas

Abstract

Three cases with avascular necrosis of the femoral head are reported of which one showed bilateral disease. Two patients with Hodgkin's disease of mixed cellularity underwent polychemotherapy; the third with gastric centroblastic non-Hodgkin lymphoma received abdominal irradiation followed by 3 courses of polychemotherapy. Total dose of prednisolone administered varied between 4,080-7,045 mg. Time elapsed between appearance of pain and significant radiologic features was several months. Patients with Hodgkin's disease were young and were both exposed to significant physical strain. Multiple factors are thought to be responsible for this late sequel of therapy in which the role of cortisone is stressed. Computed tomography is of great value in detecting disease at an early phase and depicting its real extent.
Authors:
Publication Date:
Jan 01, 1986
Product Type:
Journal Article
Reference Number:
AIX-18-005517; EDB-87-034370
Resource Relation:
Journal Name: Radiobiol., Radiother.; (German Democratic Republic); Journal Volume: 27:5
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; OSTEORADIONECROSIS; RADIOINDUCTION; CHEMOTHERAPY; DELAYED RADIATION EFFECTS; FEMUR; HODGKINS DISEASE; LYMPHOMAS; PATIENTS; PREDNISOLONE; RADIOTHERAPY; ADRENAL HORMONES; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; CORTICOSTEROIDS; DISEASES; GLUCOCORTICOIDS; HORMONES; HYDROXY COMPOUNDS; INJURIES; KETONES; LOCAL RADIATION EFFECTS; MEDICINE; NECROSIS; NEOPLASMS; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PREGNANES; RADIATION EFFECTS; RADIATION INJURIES; RADIOLOGY; SKELETAL DISEASES; SKELETON; STEROID HORMONES; STEROIDS; THERAPY; 560151* - Radiation Effects on Animals- Man
OSTI ID:
6963140
Research Organizations:
University Medical School, Pecs, Hungary. Dept. of Radiology
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: RDBGA
Submitting Site:
INIS
Size:
Pages: 571-576
Announcement Date:
Jan 01, 1987

Citation Formats

Kuhn, E, and Kovacs, A. Aseptic necrosis of the femoral head following treatment of malignant lymphomas. Germany: N. p., 1986. Web.
Kuhn, E, & Kovacs, A. Aseptic necrosis of the femoral head following treatment of malignant lymphomas. Germany.
Kuhn, E, and Kovacs, A. 1986. "Aseptic necrosis of the femoral head following treatment of malignant lymphomas." Germany.
@misc{etde_6963140,
title = {Aseptic necrosis of the femoral head following treatment of malignant lymphomas}
author = {Kuhn, E, and Kovacs, A}
abstractNote = {Three cases with avascular necrosis of the femoral head are reported of which one showed bilateral disease. Two patients with Hodgkin's disease of mixed cellularity underwent polychemotherapy; the third with gastric centroblastic non-Hodgkin lymphoma received abdominal irradiation followed by 3 courses of polychemotherapy. Total dose of prednisolone administered varied between 4,080-7,045 mg. Time elapsed between appearance of pain and significant radiologic features was several months. Patients with Hodgkin's disease were young and were both exposed to significant physical strain. Multiple factors are thought to be responsible for this late sequel of therapy in which the role of cortisone is stressed. Computed tomography is of great value in detecting disease at an early phase and depicting its real extent.}
journal = []
volume = {27:5}
journal type = {AC}
place = {Germany}
year = {1986}
month = {Jan}
}