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A longitudinal study of CMRGlu in dementia of Alzheimer type

Journal Article:

Abstract

We studied the serial changes of CMRGlu in 6 patients with dementia of Alzheimer type. All patients demonstrated moderately severe dementia at the initial PET scan. Serial PET scans were performed at an interval of 12 to 24 months. Five of the 6 patients showed a deterioration of clinical symptoms at the second scan. The global CMRGlu serially decreased in all patients. An asymmetry of CMRGlu in both the frontal and parietal regions was observed at the initial PET scan, while the direction of asymmetry was preserved at the second PET scan. The ratios (frontal/parietal and parietal/striatum) of CMRGlu showed no interval change. Therefore, CMRGlu was considered to decrease progressively throughout the entire brain in patients with moderately severe dementia of Alzheimer type. (author).
Authors:
Kuwabara, Yasuo; Ichiya, Yuichi; Ichimiya, Atsushi; Sasaki, Masayuki; Akashi, Yuko; Yoshida, Tsuyoshi; Fukumura, Toshimitsu; Masuda, Kouji [1] 
  1. Kyushu Univ., Fukuoka (Japan). Faculty of Medicine
Publication Date:
Oct 01, 1994
Product Type:
Journal Article
Reference Number:
JPN-94-012283; EDB-95-024949
Resource Relation:
Journal Name: Kaku Igaku (Japanese Journal of Nuclear Medicine); (Japan); Journal Volume: 31:10
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; POSITRON COMPUTED TOMOGRAPHY; FLUORINE 18; GLUCOSE; MENTAL DISORDERS; METABOLISM; TIME DEPENDENCE; ALDEHYDES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; BRAIN; CARBOHYDRATES; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HEXOSES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; MONOSACCHARIDES; NANOSEC LIVING RADIOISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; SACCHARIDES; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6940193
Research Organizations:
No corporate text available
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: ISSN 0022-7854; CODEN: KAIGBZ
Submitting Site:
JPN
Size:
Pages: 1255-1260
Announcement Date:
Feb 15, 1995

Journal Article:

Citation Formats

Kuwabara, Yasuo, Ichiya, Yuichi, Ichimiya, Atsushi, Sasaki, Masayuki, Akashi, Yuko, Yoshida, Tsuyoshi, Fukumura, Toshimitsu, and Masuda, Kouji. A longitudinal study of CMRGlu in dementia of Alzheimer type. Japan: N. p., 1994. Web.
Kuwabara, Yasuo, Ichiya, Yuichi, Ichimiya, Atsushi, Sasaki, Masayuki, Akashi, Yuko, Yoshida, Tsuyoshi, Fukumura, Toshimitsu, & Masuda, Kouji. A longitudinal study of CMRGlu in dementia of Alzheimer type. Japan.
Kuwabara, Yasuo, Ichiya, Yuichi, Ichimiya, Atsushi, Sasaki, Masayuki, Akashi, Yuko, Yoshida, Tsuyoshi, Fukumura, Toshimitsu, and Masuda, Kouji. 1994. "A longitudinal study of CMRGlu in dementia of Alzheimer type." Japan.
@misc{etde_6940193,
title = {A longitudinal study of CMRGlu in dementia of Alzheimer type}
author = {Kuwabara, Yasuo, Ichiya, Yuichi, Ichimiya, Atsushi, Sasaki, Masayuki, Akashi, Yuko, Yoshida, Tsuyoshi, Fukumura, Toshimitsu, and Masuda, Kouji}
abstractNote = {We studied the serial changes of CMRGlu in 6 patients with dementia of Alzheimer type. All patients demonstrated moderately severe dementia at the initial PET scan. Serial PET scans were performed at an interval of 12 to 24 months. Five of the 6 patients showed a deterioration of clinical symptoms at the second scan. The global CMRGlu serially decreased in all patients. An asymmetry of CMRGlu in both the frontal and parietal regions was observed at the initial PET scan, while the direction of asymmetry was preserved at the second PET scan. The ratios (frontal/parietal and parietal/striatum) of CMRGlu showed no interval change. Therefore, CMRGlu was considered to decrease progressively throughout the entire brain in patients with moderately severe dementia of Alzheimer type. (author).}
journal = {Kaku Igaku (Japanese Journal of Nuclear Medicine); (Japan)}
volume = {31:10}
journal type = {AC}
place = {Japan}
year = {1994}
month = {Oct}
}