You need JavaScript to view this

Use of /sup 59/Fe uptake in estimating the marrow dose in normal and splenectomized rats exposed to 1000 kVp x irradiation

Journal Article:

Abstract

The /sup 59/Fe uptake system was used to estimate the dose distribution throughout sham-operated and splenectomized rats exposed to whole-body 1000 kVp x irradiation. The marrow in the splenectomized animals was found to be slightly more radiosensitive. However, the difference between the two groups of rats was not significant. The dose distributions throughout the marrow of both groups were the same. It was concluded that splenectomy had no effect on the usefulness of this method. The method of measuring /sup 59/Fe uptake in this study used the uptake of radioiron at 6 hr post-injection and the deduction of the activity due to circulating iron. This resulted in a technique capable of measuring changes in iron uptake with midline-air-exposures of 25 R.
Authors:
Maillie, H D; Baxter, R C; Lisman, H [1] 
  1. Rochester Univ., N.Y. (USA). School of Medicine and Dentistry
Publication Date:
Nov 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-09-365639; EDB-78-092006
Resource Relation:
Journal Name: Health Phys.; (United Kingdom); Journal Volume: 33:5
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; BONE MARROW; RADIATION DOSE DISTRIBUTIONS; RADIOSENSITIVITY; IRON 59; UPTAKE; SPLENECTOMY; RADIOSENSITIVITY EFFECTS; BIOLOGICAL DOSEMETERS; INTRAVENOUS INJECTION; RADIONUCLIDE KINETICS; RATS; TRACER TECHNIQUES; WHOLE-BODY IRRADIATION; X RADIATION; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; DAYS LIVING RADIOISOTOPES; DOSEMETERS; ELECTROMAGNETIC RADIATION; EVEN-ODD NUCLEI; EXTERNAL IRRADIATION; HEMATOPOIETIC SYSTEM; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; IONIZING RADIATIONS; IRON ISOTOPES; IRRADIATION; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MEASURING INSTRUMENTS; MEDICINE; NUCLEI; ORGANS; RADIATIONS; RADIOISOTOPES; RODENTS; SURGERY; TISSUES; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals; 550601 - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6933738
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: HLTPA
Submitting Site:
INIS
Size:
Pages: 425-429
Announcement Date:
Mar 01, 1978

Journal Article:

Citation Formats

Maillie, H D, Baxter, R C, and Lisman, H. Use of /sup 59/Fe uptake in estimating the marrow dose in normal and splenectomized rats exposed to 1000 kVp x irradiation. United Kingdom: N. p., 1977. Web.
Maillie, H D, Baxter, R C, & Lisman, H. Use of /sup 59/Fe uptake in estimating the marrow dose in normal and splenectomized rats exposed to 1000 kVp x irradiation. United Kingdom.
Maillie, H D, Baxter, R C, and Lisman, H. 1977. "Use of /sup 59/Fe uptake in estimating the marrow dose in normal and splenectomized rats exposed to 1000 kVp x irradiation." United Kingdom.
@misc{etde_6933738,
title = {Use of /sup 59/Fe uptake in estimating the marrow dose in normal and splenectomized rats exposed to 1000 kVp x irradiation}
author = {Maillie, H D, Baxter, R C, and Lisman, H}
abstractNote = {The /sup 59/Fe uptake system was used to estimate the dose distribution throughout sham-operated and splenectomized rats exposed to whole-body 1000 kVp x irradiation. The marrow in the splenectomized animals was found to be slightly more radiosensitive. However, the difference between the two groups of rats was not significant. The dose distributions throughout the marrow of both groups were the same. It was concluded that splenectomy had no effect on the usefulness of this method. The method of measuring /sup 59/Fe uptake in this study used the uptake of radioiron at 6 hr post-injection and the deduction of the activity due to circulating iron. This resulted in a technique capable of measuring changes in iron uptake with midline-air-exposures of 25 R.}
journal = {Health Phys.; (United Kingdom)}
volume = {33:5}
journal type = {AC}
place = {United Kingdom}
year = {1977}
month = {Nov}
}