Abstract
The probe was a 500 bp cDNA containing exons 2-3 and 4 of the human IGF II gene. The clone was isolated by screening a human liver cDNA library with synthetic oligonucleotides. Eco RI digestion of genomic DNA and hybridization with the IGF II probe detects a two allele polymorphism with allelic fragments of 13.5 kb and 10.5 kb. The frequency was studied 38 unrelated Caucasians: Human IGF II gene was localized on the short arm of chromosome 11 (p15) by in situ hybridization. Codominant segregation was observed in 2 Caucasian families (10 individuals).
Citation Formats
Cocozza, S, Garofalo, S, Robledo, R, Monticelli, A, Conti, A, Chiarotti, L, Frunzio, R, Bruni, C B, and Varrone, S.
Eco RI RFLP in the human IGF II gene.
United Kingdom: N. p.,
1988.
Web.
doi:10.1093/nar/16.6.2737.
Cocozza, S, Garofalo, S, Robledo, R, Monticelli, A, Conti, A, Chiarotti, L, Frunzio, R, Bruni, C B, & Varrone, S.
Eco RI RFLP in the human IGF II gene.
United Kingdom.
https://doi.org/10.1093/nar/16.6.2737
Cocozza, S, Garofalo, S, Robledo, R, Monticelli, A, Conti, A, Chiarotti, L, Frunzio, R, Bruni, C B, and Varrone, S.
1988.
"Eco RI RFLP in the human IGF II gene."
United Kingdom.
https://doi.org/10.1093/nar/16.6.2737.
@misc{etde_6924510,
title = {Eco RI RFLP in the human IGF II gene}
author = {Cocozza, S, Garofalo, S, Robledo, R, Monticelli, A, Conti, A, Chiarotti, L, Frunzio, R, Bruni, C B, and Varrone, S}
abstractNote = {The probe was a 500 bp cDNA containing exons 2-3 and 4 of the human IGF II gene. The clone was isolated by screening a human liver cDNA library with synthetic oligonucleotides. Eco RI digestion of genomic DNA and hybridization with the IGF II probe detects a two allele polymorphism with allelic fragments of 13.5 kb and 10.5 kb. The frequency was studied 38 unrelated Caucasians: Human IGF II gene was localized on the short arm of chromosome 11 (p15) by in situ hybridization. Codominant segregation was observed in 2 Caucasian families (10 individuals).}
doi = {10.1093/nar/16.6.2737}
journal = []
volume = {16:6}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Mar}
}
title = {Eco RI RFLP in the human IGF II gene}
author = {Cocozza, S, Garofalo, S, Robledo, R, Monticelli, A, Conti, A, Chiarotti, L, Frunzio, R, Bruni, C B, and Varrone, S}
abstractNote = {The probe was a 500 bp cDNA containing exons 2-3 and 4 of the human IGF II gene. The clone was isolated by screening a human liver cDNA library with synthetic oligonucleotides. Eco RI digestion of genomic DNA and hybridization with the IGF II probe detects a two allele polymorphism with allelic fragments of 13.5 kb and 10.5 kb. The frequency was studied 38 unrelated Caucasians: Human IGF II gene was localized on the short arm of chromosome 11 (p15) by in situ hybridization. Codominant segregation was observed in 2 Caucasian families (10 individuals).}
doi = {10.1093/nar/16.6.2737}
journal = []
volume = {16:6}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Mar}
}