Abstract
The single breath measurement with /sup 11/CO/sub 2/, /sup 11/CO and /sup 13/N-N composed of inhalation system and a coincidence positron camera interfaced with an on-line computer system has been used to evaluated regional pulmonary function in two normal volunteers and four patients with chronic obstructive pulmonary disease (COPD). In serial images of normal subjects after single inhalation of /sup 11/CO/sub 2/, the appearance time of the heart was within about 10 - 20 seconds and the radioactivity at heart area remained relatively high compared with lung fields. However in some patients with COPD, the heart appearance time was delayed and the hypo-ventilated lung area became gradually hot during the wash-out phase. The heart appearance time after an inspiration of /sup 11/CO was within 10 - 20 seconds in normal subject. In contrast, the appearance time was remarkably prolonged in the patients with disturbance of diffusion capacity. Immediately after single breath of /sup 13/N-N in the patient with COPD the well ventilated lung area was revealed as a region of high radioactivity and the distribution of the slow space was showed in the late phase of wash out. These findings should have patho-physiological diagnostic usefulness, especially for the patients with
More>>
Kimura, K;
Rikitake, T;
Hasegawa, S;
[1]
Matsumoto, T;
Tateno, Y
- Tsukuba Univ., Sakura, Ibaraki (Japan)
Citation Formats
Kimura, K, Rikitake, T, Hasegawa, S, Matsumoto, T, and Tateno, Y.
Clinical application of dynamic lung imaging by the single breath measurement with carbon-11-labeled CO/sub 2/, CO and nitrogen-13-labeled N/sub 2/.
Japan: N. p.,
1979.
Web.
Kimura, K, Rikitake, T, Hasegawa, S, Matsumoto, T, & Tateno, Y.
Clinical application of dynamic lung imaging by the single breath measurement with carbon-11-labeled CO/sub 2/, CO and nitrogen-13-labeled N/sub 2/.
Japan.
Kimura, K, Rikitake, T, Hasegawa, S, Matsumoto, T, and Tateno, Y.
1979.
"Clinical application of dynamic lung imaging by the single breath measurement with carbon-11-labeled CO/sub 2/, CO and nitrogen-13-labeled N/sub 2/."
Japan.
@misc{etde_6886680,
title = {Clinical application of dynamic lung imaging by the single breath measurement with carbon-11-labeled CO/sub 2/, CO and nitrogen-13-labeled N/sub 2/}
author = {Kimura, K, Rikitake, T, Hasegawa, S, Matsumoto, T, and Tateno, Y}
abstractNote = {The single breath measurement with /sup 11/CO/sub 2/, /sup 11/CO and /sup 13/N-N composed of inhalation system and a coincidence positron camera interfaced with an on-line computer system has been used to evaluated regional pulmonary function in two normal volunteers and four patients with chronic obstructive pulmonary disease (COPD). In serial images of normal subjects after single inhalation of /sup 11/CO/sub 2/, the appearance time of the heart was within about 10 - 20 seconds and the radioactivity at heart area remained relatively high compared with lung fields. However in some patients with COPD, the heart appearance time was delayed and the hypo-ventilated lung area became gradually hot during the wash-out phase. The heart appearance time after an inspiration of /sup 11/CO was within 10 - 20 seconds in normal subject. In contrast, the appearance time was remarkably prolonged in the patients with disturbance of diffusion capacity. Immediately after single breath of /sup 13/N-N in the patient with COPD the well ventilated lung area was revealed as a region of high radioactivity and the distribution of the slow space was showed in the late phase of wash out. These findings should have patho-physiological diagnostic usefulness, especially for the patients with COPD and fibrosing lung disease.}
journal = []
volume = {16:6}
journal type = {AC}
place = {Japan}
year = {1979}
month = {Sep}
}
title = {Clinical application of dynamic lung imaging by the single breath measurement with carbon-11-labeled CO/sub 2/, CO and nitrogen-13-labeled N/sub 2/}
author = {Kimura, K, Rikitake, T, Hasegawa, S, Matsumoto, T, and Tateno, Y}
abstractNote = {The single breath measurement with /sup 11/CO/sub 2/, /sup 11/CO and /sup 13/N-N composed of inhalation system and a coincidence positron camera interfaced with an on-line computer system has been used to evaluated regional pulmonary function in two normal volunteers and four patients with chronic obstructive pulmonary disease (COPD). In serial images of normal subjects after single inhalation of /sup 11/CO/sub 2/, the appearance time of the heart was within about 10 - 20 seconds and the radioactivity at heart area remained relatively high compared with lung fields. However in some patients with COPD, the heart appearance time was delayed and the hypo-ventilated lung area became gradually hot during the wash-out phase. The heart appearance time after an inspiration of /sup 11/CO was within 10 - 20 seconds in normal subject. In contrast, the appearance time was remarkably prolonged in the patients with disturbance of diffusion capacity. Immediately after single breath of /sup 13/N-N in the patient with COPD the well ventilated lung area was revealed as a region of high radioactivity and the distribution of the slow space was showed in the late phase of wash out. These findings should have patho-physiological diagnostic usefulness, especially for the patients with COPD and fibrosing lung disease.}
journal = []
volume = {16:6}
journal type = {AC}
place = {Japan}
year = {1979}
month = {Sep}
}