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Lethal doses of ionizing radiation versus endogenous level of superoxide dismutase

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Abstract

The stability of superoxide dismutase (SOD) as well as its activity distribution in a human population were investigated. The SOD activity level of the erythrocytes proved to be an index for the endogenous SOD activity in the whole body. In a rat population, having similar SOD frequency distribution as a human population, the mortality due to acute irradiation depended on the SOD level; after a single acute dose approximating the lethal dose (LD/sub 50/30/) the survival depended distinctly on the endogenous SOD activity level.
Authors:
Lipecka, K; Domanski, T; Dniaszewska, K; Grabowska, B; Pietrowicz, D; Lindner, P; Cisowska, B; Gorski, H [1] 
  1. Military Medical Academy, Lodz (Poland). Inst. of Occupational Medicine
Publication Date:
Jun 22, 1982
Product Type:
Journal Article
Reference Number:
AIX-13-713960; EDB-83-028132
Resource Relation:
Journal Name: Stud. Biophys.; (German Democratic Republic); Journal Volume: 89:1
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ERYTHROCYTES; BIOLOGICAL RADIATION EFFECTS; OXIDOREDUCTASES; X RADIATION; LETHAL RADIATION DOSE; ACUTE IRRADIATION; BLOOD; CATALYSIS; COMPARATIVE EVALUATIONS; FEMALES; GUINEA PIGS; LIVER; LUNGS; MALES; MEN; METABOLISM; MORTALITY; MUSCLES; PEROXIDES; RABBITS; RATS; SPLEEN; SURVIVAL TIME; WOMEN; ACUTE EXPOSURE; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD CELLS; BODY; BODY FLUIDS; DIGESTIVE SYSTEM; DOSES; ELECTROMAGNETIC RADIATION; ENZYMES; GLANDS; IONIZING RADIATIONS; IRRADIATION; LETHAL DOSES; MAMMALS; MAN; MATERIALS; ORGANS; OXYGEN COMPOUNDS; PRIMATES; RADIATION DOSES; RADIATION EFFECTS; RADIATIONS; RESPIRATORY SYSTEM; RODENTS; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
6866826
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: STBIB
Submitting Site:
HEDB
Size:
Pages: 57-64
Announcement Date:
Nov 01, 1982

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Citation Formats

Lipecka, K, Domanski, T, Dniaszewska, K, Grabowska, B, Pietrowicz, D, Lindner, P, Cisowska, B, and Gorski, H. Lethal doses of ionizing radiation versus endogenous level of superoxide dismutase. Germany: N. p., 1982. Web.
Lipecka, K, Domanski, T, Dniaszewska, K, Grabowska, B, Pietrowicz, D, Lindner, P, Cisowska, B, & Gorski, H. Lethal doses of ionizing radiation versus endogenous level of superoxide dismutase. Germany.
Lipecka, K, Domanski, T, Dniaszewska, K, Grabowska, B, Pietrowicz, D, Lindner, P, Cisowska, B, and Gorski, H. 1982. "Lethal doses of ionizing radiation versus endogenous level of superoxide dismutase." Germany.
@misc{etde_6866826,
title = {Lethal doses of ionizing radiation versus endogenous level of superoxide dismutase}
 author = {Lipecka, K, Domanski, T, Dniaszewska, K, Grabowska, B, Pietrowicz, D, Lindner, P, Cisowska, B, and Gorski, H}
 abstractNote = {The stability of superoxide dismutase (SOD) as well as its activity distribution in a human population were investigated. The SOD activity level of the erythrocytes proved to be an index for the endogenous SOD activity in the whole body. In a rat population, having similar SOD frequency distribution as a human population, the mortality due to acute irradiation depended on the SOD level; after a single acute dose approximating the lethal dose (LD/sub 50/30/) the survival depended distinctly on the endogenous SOD activity level.}
 journal = []
 volume = {89:1}
 journal type = {AC}
 place = {Germany}
 year = {1982}
 month = {Jun}
 }