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CT findings in brain edema following the administration of corticosteroids

Journal Article:

Abstract

Computed tomography (CT) is the first noninvasive method available for directly visualizing brain edema in man. On CT scans perifocal edema is shown as an area of low density surrounding a lesion. The purpose of this report is to evaluate the effect of corticosteroids on brain edema as seen by CT (HITACHI CT-H 250). Nine patients with brain-tumor and one with brain-abscess were treated with betamethasone for about ten days (dosage started with 12 - 16 mg/day, and tapered). In eight cases, and improvement in the neurological findings was observed. An impressive reduction of peritumoral edema was shown on CT scans in six of these eight cases. There was, however, no significant correlation between the degree of the reduction of edema on CT and that of the improvement in neurological findings. The mode of the CT number in the region of edema did not differ significantly between pre- and post-steroid treatment in the cases showing a recognizable reduction of edema on CT. This failure to change is probably due to the insufficient mechanical accuracy of the CT scanner at the present stage of technology. Through our experiences, it seems that CT is one of the most promising tools for a  More>>
Authors:
Seki, Y; Kumagai, N; Aiba, T [1] 
  1. Toranomon Hospital, Tokyo (Japan)
Publication Date:
Mar 01, 1979
Product Type:
Journal Article
Reference Number:
AIX-11-562289; EDB-81-012415
Resource Relation:
Journal Name: CT Kenkyu.; (Japan); Journal Volume: 1:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; BRAIN; CAT SCANNING; EDEMA; ABSCESSES; CHEMOTHERAPY; COMPUTERIZED TOMOGRAPHY; CORTICOSTEROIDS; DIAGNOSIS; MENINGES; METASTASES; NEOPLASMS; NERVOUS SYSTEM DISEASES; PATIENTS; TIME DEPENDENCE; ADRENAL HORMONES; BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; HORMONES; HYDROXY COMPOUNDS; IMAGE PROCESSING; KETONES; MEMBRANES; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; PREGNANES; PROCESSING; STEROID HORMONES; STEROIDS; SYMPTOMS; THERAPY; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6855444
Country of Origin:
Japan
Language:
Japanese
Submitting Site:
INIS
Size:
Pages: 417-423
Announcement Date:

Journal Article:

Citation Formats

Seki, Y, Kumagai, N, and Aiba, T. CT findings in brain edema following the administration of corticosteroids. Japan: N. p., 1979. Web.
Seki, Y, Kumagai, N, & Aiba, T. CT findings in brain edema following the administration of corticosteroids. Japan.
Seki, Y, Kumagai, N, and Aiba, T. 1979. "CT findings in brain edema following the administration of corticosteroids." Japan.
@misc{etde_6855444,
title = {CT findings in brain edema following the administration of corticosteroids}
author = {Seki, Y, Kumagai, N, and Aiba, T}
abstractNote = {Computed tomography (CT) is the first noninvasive method available for directly visualizing brain edema in man. On CT scans perifocal edema is shown as an area of low density surrounding a lesion. The purpose of this report is to evaluate the effect of corticosteroids on brain edema as seen by CT (HITACHI CT-H 250). Nine patients with brain-tumor and one with brain-abscess were treated with betamethasone for about ten days (dosage started with 12 - 16 mg/day, and tapered). In eight cases, and improvement in the neurological findings was observed. An impressive reduction of peritumoral edema was shown on CT scans in six of these eight cases. There was, however, no significant correlation between the degree of the reduction of edema on CT and that of the improvement in neurological findings. The mode of the CT number in the region of edema did not differ significantly between pre- and post-steroid treatment in the cases showing a recognizable reduction of edema on CT. This failure to change is probably due to the insufficient mechanical accuracy of the CT scanner at the present stage of technology. Through our experiences, it seems that CT is one of the most promising tools for a dynamic study of brain edema in man.}
journal = {CT Kenkyu.; (Japan)}
volume = {1:3}
journal type = {AC}
place = {Japan}
year = {1979}
month = {Mar}
}