Abstract
pESR-2, a 2.1 kb partial cDNA containing the entire translated sequence of the human estrogen receptor mRNA isolated from MCF-7 human breast cancer cells, was subcloned in the Eco RI site of pBR322. PssI (PuGGNCCPy) identifies a single two-allele polymorphism with bands at either 1.7 or 1.4 kb, as well as invariant bands at 12.6, 9.3, 4.1, 3.7, 2.4, 2.2, and 1.2 kb. Its frequency was studied in 77 unrelated North American Caucasians. The human estrogen receptor gene has been localized to 6q24 -- q27 by in situ hybridization. Co-dominant segregation is demonstrated in one family (8 individuals).
Coleman, R T;
Taylor, J E;
Frossard, P M;
[1]
Shine, J J
[2]
- California Biotechnology Inc., Mountain View, CA (USA)
- Garvan Institute, Darlinghurst (Australia)
Citation Formats
Coleman, R T, Taylor, J E, Frossard, P M, and Shine, J J.
Human estrogen receptor (ESR) gene locus: PssI dimorphism.
United Kingdom: N. p.,
1988.
Web.
doi:10.1093/nar/16.14.7208.
Coleman, R T, Taylor, J E, Frossard, P M, & Shine, J J.
Human estrogen receptor (ESR) gene locus: PssI dimorphism.
United Kingdom.
https://doi.org/10.1093/nar/16.14.7208
Coleman, R T, Taylor, J E, Frossard, P M, and Shine, J J.
1988.
"Human estrogen receptor (ESR) gene locus: PssI dimorphism."
United Kingdom.
https://doi.org/10.1093/nar/16.14.7208.
@misc{etde_6829393,
title = {Human estrogen receptor (ESR) gene locus: PssI dimorphism}
author = {Coleman, R T, Taylor, J E, Frossard, P M, and Shine, J J}
abstractNote = {pESR-2, a 2.1 kb partial cDNA containing the entire translated sequence of the human estrogen receptor mRNA isolated from MCF-7 human breast cancer cells, was subcloned in the Eco RI site of pBR322. PssI (PuGGNCCPy) identifies a single two-allele polymorphism with bands at either 1.7 or 1.4 kb, as well as invariant bands at 12.6, 9.3, 4.1, 3.7, 2.4, 2.2, and 1.2 kb. Its frequency was studied in 77 unrelated North American Caucasians. The human estrogen receptor gene has been localized to 6q24 -- q27 by in situ hybridization. Co-dominant segregation is demonstrated in one family (8 individuals).}
doi = {10.1093/nar/16.14.7208}
journal = []
volume = {16:14B}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Jul}
}
title = {Human estrogen receptor (ESR) gene locus: PssI dimorphism}
author = {Coleman, R T, Taylor, J E, Frossard, P M, and Shine, J J}
abstractNote = {pESR-2, a 2.1 kb partial cDNA containing the entire translated sequence of the human estrogen receptor mRNA isolated from MCF-7 human breast cancer cells, was subcloned in the Eco RI site of pBR322. PssI (PuGGNCCPy) identifies a single two-allele polymorphism with bands at either 1.7 or 1.4 kb, as well as invariant bands at 12.6, 9.3, 4.1, 3.7, 2.4, 2.2, and 1.2 kb. Its frequency was studied in 77 unrelated North American Caucasians. The human estrogen receptor gene has been localized to 6q24 -- q27 by in situ hybridization. Co-dominant segregation is demonstrated in one family (8 individuals).}
doi = {10.1093/nar/16.14.7208}
journal = []
volume = {16:14B}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Jul}
}