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RFLP for Duchenne muscular dystrophy cDNA clone 44-1

Abstract

Clone 44-1 is one of six cDNA clones which comprise the cDNA for the Duchenne muscular dystrophy gene. It is a 0.9kb fragment in the EcoR1 site of Bluescript. Taq1 (TlCGA) identifies two alleles with bands at 6.8 and 5.7kb, as well as four constant bands at 4.8, 3.9, 3.5 and 2.5kb. Its frequency was studied in 62 unrelated individuals. Mendelian inheritance was demonstrated in one three generation and three two generation informative families, 26 individuals. There were no problems on RFLP analysis under normal stringency conditions.
Authors:
Laing, N G; Siddique, T; Bartlett, R J; Yamaoka, L H; Chen, J C; Walker, A P; Hung, W Y; Roses, A D [1] 
  1. Duke Univ. Medical Center, Durham, NC (USA)
Publication Date:
Jul 25, 1988
Product Type:
Journal Article
Reference Number:
EDB-90-096463
Resource Relation:
Journal Name: Nucleic Acids Research; (UK); Journal Volume: 16:14B
Subject:
59 BASIC BIOLOGICAL SCIENCES; NERVOUS SYSTEM DISEASES; GENETICS; RECOMBINANT DNA; RFLPS; GENES; HEREDITARY DISEASES; HUMAN POPULATIONS; PHOSPHORUS 32; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGY; DAYS LIVING RADIOISOTOPES; DISEASES; DNA; ISOTOPES; LIGHT NUCLEI; NUCLEI; NUCLEIC ACIDS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PHOSPHORUS ISOTOPES; POPULATIONS; RADIOISOTOPES; 550201* - Biochemistry- Tracer Techniques
OSTI ID:
6829386
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0305-1048; CODEN: NARHA
Submitting Site:
JMT
Size:
Pages: 7209-7210
Announcement Date:
Jul 01, 1990

Citation Formats

Laing, N G, Siddique, T, Bartlett, R J, Yamaoka, L H, Chen, J C, Walker, A P, Hung, W Y, and Roses, A D. RFLP for Duchenne muscular dystrophy cDNA clone 44-1. United Kingdom: N. p., 1988. Web. doi:10.1093/nar/16.14.7209.
Laing, N G, Siddique, T, Bartlett, R J, Yamaoka, L H, Chen, J C, Walker, A P, Hung, W Y, & Roses, A D. RFLP for Duchenne muscular dystrophy cDNA clone 44-1. United Kingdom. https://doi.org/10.1093/nar/16.14.7209
Laing, N G, Siddique, T, Bartlett, R J, Yamaoka, L H, Chen, J C, Walker, A P, Hung, W Y, and Roses, A D. 1988. "RFLP for Duchenne muscular dystrophy cDNA clone 44-1." United Kingdom. https://doi.org/10.1093/nar/16.14.7209.
@misc{etde_6829386,
title = {RFLP for Duchenne muscular dystrophy cDNA clone 44-1}
author = {Laing, N G, Siddique, T, Bartlett, R J, Yamaoka, L H, Chen, J C, Walker, A P, Hung, W Y, and Roses, A D}
abstractNote = {Clone 44-1 is one of six cDNA clones which comprise the cDNA for the Duchenne muscular dystrophy gene. It is a 0.9kb fragment in the EcoR1 site of Bluescript. Taq1 (TlCGA) identifies two alleles with bands at 6.8 and 5.7kb, as well as four constant bands at 4.8, 3.9, 3.5 and 2.5kb. Its frequency was studied in 62 unrelated individuals. Mendelian inheritance was demonstrated in one three generation and three two generation informative families, 26 individuals. There were no problems on RFLP analysis under normal stringency conditions.}
doi = {10.1093/nar/16.14.7209}
journal = []
volume = {16:14B}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Jul}
}