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Scintigraphic detection of inflammatory heart disease

Abstract

Inflammatory diseases of the heart encompass myocarditis, endocarditis and pericarditis. This paper discusses the diagnostic potential of scintigraphy in these entities. In myocarditis, indium-111 antimyosin Fab imaging can visualize active myocyte damage and thus contribute substantially to the diagnosis. Antimyosin uptake is also seen in a large subset of patients with dilated cardiomyopathy, indicating ongoing myocyte injury in these cases. In endocarditis, immunoscintigraphy using monoclonal technetium-99m-labelled antigranulocyte antibodies provides useful diagnostic information in patients with equivocal echocardiographic findings. Immunoscintigraphy seems to indicate the floridity of the inflammatory process in endocarditis and may be used to monitor antibiotic therapy. In pericarditis, the clinical value of scintigraphy has not been convincingly demonstrated. (orig.)
Authors:
Morguet, A J; [1]  Munz, D L; [2]  Kreuzer, H; [1]  Emrich, D [2] 
  1. Dept. of Cardiology and Pulmonology, Centre of Internal Medicine, Georg August Univ., Goettingen (Germany)
  2. Dept. of Nuclear Medicine, Centre of Radiology, Georg August Univ., Goettingen (Germany)
Publication Date:
Jul 01, 1994
Product Type:
Journal Article
Reference Number:
DEN-94-0FJ621; EDB-94-170301
Resource Relation:
Journal Name: European Journal of Nuclear Medicine; (Germany); Journal Volume: 21:7
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HEART; INFLAMMATION; RADIOIMMUNODETECTION; SCINTISCANNING; ANTIBODIES; DIAGNOSIS; IMAGES; LEUKOCYTES; PATIENTS; TECHNETIUM 99; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CARDIOVASCULAR SYSTEM; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PATHOLOGICAL CHANGES; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; TRACER TECHNIQUES; YEARS LIVING RADIOI; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6810457
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0340-6997; CODEN: EJNMD9
Submitting Site:
DEN
Size:
Pages: 666-674
Announcement Date:

Citation Formats

Morguet, A J, Munz, D L, Kreuzer, H, and Emrich, D. Scintigraphic detection of inflammatory heart disease. Germany: N. p., 1994. Web. doi:10.1007/BF00285591.
Morguet, A J, Munz, D L, Kreuzer, H, & Emrich, D. Scintigraphic detection of inflammatory heart disease. Germany. doi:10.1007/BF00285591.
Morguet, A J, Munz, D L, Kreuzer, H, and Emrich, D. 1994. "Scintigraphic detection of inflammatory heart disease." Germany. doi:10.1007/BF00285591. https://www.osti.gov/servlets/purl/10.1007/BF00285591.
@misc{etde_6810457,
title = {Scintigraphic detection of inflammatory heart disease}
author = {Morguet, A J, Munz, D L, Kreuzer, H, and Emrich, D}
abstractNote = {Inflammatory diseases of the heart encompass myocarditis, endocarditis and pericarditis. This paper discusses the diagnostic potential of scintigraphy in these entities. In myocarditis, indium-111 antimyosin Fab imaging can visualize active myocyte damage and thus contribute substantially to the diagnosis. Antimyosin uptake is also seen in a large subset of patients with dilated cardiomyopathy, indicating ongoing myocyte injury in these cases. In endocarditis, immunoscintigraphy using monoclonal technetium-99m-labelled antigranulocyte antibodies provides useful diagnostic information in patients with equivocal echocardiographic findings. Immunoscintigraphy seems to indicate the floridity of the inflammatory process in endocarditis and may be used to monitor antibiotic therapy. In pericarditis, the clinical value of scintigraphy has not been convincingly demonstrated. (orig.)}
doi = {10.1007/BF00285591}
journal = {European Journal of Nuclear Medicine; (Germany)}
volume = {21:7}
journal type = {AC}
place = {Germany}
year = {1994}
month = {Jul}
}