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A TaqI RFLP identified at the retinoblastoma locus on chromosome 13

Abstract

Probe D95HS0.5 is a 0.6 kb fragment subcloned into Bluescribe a pUC19 derivative from a bacterio phage library isolated by a cDNA probe of the retinoblastoma gene. The fragment is released with the enzymes HindIII and SaII. TaqI identifies a 2 allele polymorphism with a band at 2.1 kb and 1.8 kb with a frequency of 0.97 and 0.03 respectively. There are no constant bands. The probe was assigned to chromosome 13 using a linkage analysis with retinoblastoma. Co-dominant inheritance was shown in 3 CEPH pedigrees.
Authors:
Shiang, R; Murray, J C; [1]  Wiggs, J; Dryja, T [2] 
  1. Univ. of Iowa, Iowa City (USA)
  2. Massachusetts Eye and Ear Infirmary, Boston (USA)
Publication Date:
Sep 26, 1988
Product Type:
Journal Article
Reference Number:
EDB-90-159223
Resource Relation:
Journal Name: Nucleic Acids Research; (UK); Journal Volume: 16:18
Subject:
59 BASIC BIOLOGICAL SCIENCES; ONCOGENES; DNA SEQUENCING; RFLPS; DNA HYBRIDIZATION; BACTERIOPHAGES; GENETIC MAPPING; HETEROCHROMOSOMES; HUMAN POPULATIONS; MAN; NEOPLASMS; PLASMIDS; RECOMBINANT DNA; ANIMALS; CELL CONSTITUENTS; CHROMOSOMES; DISEASES; DNA; GENES; HYBRIDIZATION; MAMMALS; MAPPING; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PARASITES; POPULATIONS; PRIMATES; STRUCTURAL CHEMICAL ANALYSIS; VERTEBRATES; VIRUSES; 550200* - Biochemistry
OSTI ID:
6797072
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0305-1048; CODEN: NARHA
Submitting Site:
JMT
Size:
Pages: 9069
Announcement Date:
Nov 01, 1990

Citation Formats

Shiang, R, Murray, J C, Wiggs, J, and Dryja, T. A TaqI RFLP identified at the retinoblastoma locus on chromosome 13. United Kingdom: N. p., 1988. Web. doi:10.1093/nar/16.18.9069.
Shiang, R, Murray, J C, Wiggs, J, & Dryja, T. A TaqI RFLP identified at the retinoblastoma locus on chromosome 13. United Kingdom. https://doi.org/10.1093/nar/16.18.9069
Shiang, R, Murray, J C, Wiggs, J, and Dryja, T. 1988. "A TaqI RFLP identified at the retinoblastoma locus on chromosome 13." United Kingdom. https://doi.org/10.1093/nar/16.18.9069.
@misc{etde_6797072,
title = {A TaqI RFLP identified at the retinoblastoma locus on chromosome 13}
author = {Shiang, R, Murray, J C, Wiggs, J, and Dryja, T}
abstractNote = {Probe D95HS0.5 is a 0.6 kb fragment subcloned into Bluescribe a pUC19 derivative from a bacterio phage library isolated by a cDNA probe of the retinoblastoma gene. The fragment is released with the enzymes HindIII and SaII. TaqI identifies a 2 allele polymorphism with a band at 2.1 kb and 1.8 kb with a frequency of 0.97 and 0.03 respectively. There are no constant bands. The probe was assigned to chromosome 13 using a linkage analysis with retinoblastoma. Co-dominant inheritance was shown in 3 CEPH pedigrees.}
doi = {10.1093/nar/16.18.9069}
journal = []
volume = {16:18}
journal type = {AC}
place = {United Kingdom}
year = {1988}
month = {Sep}
}