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Quantitative evaluation of inhaled radioactive aerosol deposition patterns in the lungs in obstructive airways disease

Abstract

Uneven distribution of inhaled aerosol in the lungs is the characteristics of obstructive airways disease such as chronic bronchitis and pulmonary emphysema, and has been classified typically into peripheral and central deposition patterns, respectively by visual inspection, whereas in the normal the distribution is homogeneous throughout the lungs. The purpose of the present study was to analyse the distribution of inhaled radioactivity in the lungs by way of matrixes by a computer. The seemingly homogeneous distribution pattern in normal subjects has been found to indicate a gradual change in count profile between the neighboring matrixes. The peripheral pattern indicates the patchy presence of small number of matrixes with excessive radioactivity throughout the lungs, and the central pattern, the presence of matrixes of excessive radioactivity along the major central airways forming a comma-like configuration superimposed on the peripheral pattern. Our computer analysis has a potentiality to characterize obstructive airways disease for a better understanding of their pathophysiology, which is not feasible by a simple visual inspection of images on a polaroid picture.
Publication Date:
Dec 01, 1985
Product Type:
Journal Article
Reference Number:
AIX-18-032000; EDB-87-058389
Resource Relation:
Journal Name: Nippon Rinsho Gazo Igaku Zasshi; (Japan); Journal Volume: 4:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; LUNGS; SCINTISCANNING; TECHNETIUM 99; BIOLOGICAL FUNCTIONS; DEPOSITION; ERRORS; IMAGES; INHALATION; PATIENTS; RESPIRATORY SYSTEM DISEASES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DISEASES; FUNCTIONS; HOURS LIVING RADIOISOTOPES; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6796004
Research Organizations:
Tohoku Univ., Sendai, Japan. Research Inst. for Tuberculosis and Cancer
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NRGZE
Submitting Site:
INIS
Size:
Pages: 1059-1066
Announcement Date:
Apr 01, 1987

Citation Formats

Teshima, Takeo, Isawa, Toyoharu, Hirano, Tomio, Ebina, Akio, Shiraishi, Koichiro, and Konno, Kiyoshi. Quantitative evaluation of inhaled radioactive aerosol deposition patterns in the lungs in obstructive airways disease. Japan: N. p., 1985. Web.
Teshima, Takeo, Isawa, Toyoharu, Hirano, Tomio, Ebina, Akio, Shiraishi, Koichiro, & Konno, Kiyoshi. Quantitative evaluation of inhaled radioactive aerosol deposition patterns in the lungs in obstructive airways disease. Japan.
Teshima, Takeo, Isawa, Toyoharu, Hirano, Tomio, Ebina, Akio, Shiraishi, Koichiro, and Konno, Kiyoshi. 1985. "Quantitative evaluation of inhaled radioactive aerosol deposition patterns in the lungs in obstructive airways disease." Japan.
@misc{etde_6796004,
title = {Quantitative evaluation of inhaled radioactive aerosol deposition patterns in the lungs in obstructive airways disease}
author = {Teshima, Takeo, Isawa, Toyoharu, Hirano, Tomio, Ebina, Akio, Shiraishi, Koichiro, and Konno, Kiyoshi}
abstractNote = {Uneven distribution of inhaled aerosol in the lungs is the characteristics of obstructive airways disease such as chronic bronchitis and pulmonary emphysema, and has been classified typically into peripheral and central deposition patterns, respectively by visual inspection, whereas in the normal the distribution is homogeneous throughout the lungs. The purpose of the present study was to analyse the distribution of inhaled radioactivity in the lungs by way of matrixes by a computer. The seemingly homogeneous distribution pattern in normal subjects has been found to indicate a gradual change in count profile between the neighboring matrixes. The peripheral pattern indicates the patchy presence of small number of matrixes with excessive radioactivity throughout the lungs, and the central pattern, the presence of matrixes of excessive radioactivity along the major central airways forming a comma-like configuration superimposed on the peripheral pattern. Our computer analysis has a potentiality to characterize obstructive airways disease for a better understanding of their pathophysiology, which is not feasible by a simple visual inspection of images on a polaroid picture.}
journal = []
volume = {4:4}
journal type = {AC}
place = {Japan}
year = {1985}
month = {Dec}
}