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/sup 14/C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease

Journal Article:

Abstract

D-galactose metabolism and demethylation of aminopyrine by healthy controls and patients with chronic active hepatitis (CAH) and cirrhosis (Ci), were assessed by a breath analysis technique measuring /sup 14/CO2 exhalation after oral ingestion of /sup 14/C-D-galactose or /sup 14/C-aminopyrine. Patients with CAH and Ci exhibited decreased /sup 14/CO2-exhalation rates following /sup 14/-D-galactose or /sup 14/C-aminopyrine. D-galactose oxidation capacity of the liver can be assessed by a breath analysis technique in analogy to the demethylating function for aminopyrine. The ordinary oral D-galactose tolerance test seems, however, superior in comparison to the /sup 14/C-D-galactose tolerance test, in discriminating between healthy controls and patients with chronic liver disease.
Publication Date:
Jan 01, 1978
Product Type:
Journal Article
Reference Number:
EDB-81-012527
Resource Relation:
Journal Name: Digestion; (Switzerland); Journal Volume: 17:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; DIGESTIVE SYSTEM DISEASES; DIAGNOSTIC TECHNIQUES; HEPATITIS; BREATH; CARBON 14 COMPOUNDS; CARBON DIOXIDE; GALACTOSE; INGESTION; LIVER; METABOLISM; PATIENTS; TRACER TECHNIQUES; ALDEHYDES; BODY; CARBOHYDRATES; CARBON COMPOUNDS; CARBON OXIDES; CHALCOGENIDES; DIGESTIVE SYSTEM; DISEASES; GLANDS; HEXOSES; INTAKE; ISOTOPE APPLICATIONS; LABELLED COMPOUNDS; MONOSACCHARIDES; ORGANIC COMPOUNDS; ORGANS; OXIDES; OXYGEN COMPOUNDS; SACCHARIDES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6794059
Research Organizations:
Univ. of Goettingen, Germany
Country of Origin:
Switzerland
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: DIGEB
Submitting Site:
TIC
Size:
Pages: 410-418
Announcement Date:

Journal Article:

Citation Formats

Caspary, W F, and Schaffer, J. /sup 14/C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease. Switzerland: N. p., 1978. Web.
Caspary, W F, & Schaffer, J. /sup 14/C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease. Switzerland.
Caspary, W F, and Schaffer, J. 1978. "/sup 14/C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease." Switzerland.
@misc{etde_6794059,
title = {/sup 14/C-D-galactose breath test for evaluation of liver function in patients with chronic liver disease}
author = {Caspary, W F, and Schaffer, J}
abstractNote = {D-galactose metabolism and demethylation of aminopyrine by healthy controls and patients with chronic active hepatitis (CAH) and cirrhosis (Ci), were assessed by a breath analysis technique measuring /sup 14/CO2 exhalation after oral ingestion of /sup 14/C-D-galactose or /sup 14/C-aminopyrine. Patients with CAH and Ci exhibited decreased /sup 14/CO2-exhalation rates following /sup 14/-D-galactose or /sup 14/C-aminopyrine. D-galactose oxidation capacity of the liver can be assessed by a breath analysis technique in analogy to the demethylating function for aminopyrine. The ordinary oral D-galactose tolerance test seems, however, superior in comparison to the /sup 14/C-D-galactose tolerance test, in discriminating between healthy controls and patients with chronic liver disease.}
journal = {Digestion; (Switzerland)}
volume = {17:5}
journal type = {AC}
place = {Switzerland}
year = {1978}
month = {Jan}
}