Abstract
Bouvardin, a cyclic hexapeptide and a new antineoplastic, protein synthesis inhibitor, was studied for its effects on bacterial growth and metabolism. E.coli and S.aureus as representative types of gram-negative and gram-positive bacteria respectively were used for these studies. Garamycin and kanamycin were also employed as known antibiotics to compare their effects with bouvardin. Both garamycin and kanamycin markedly reduced /sup 14/C-glucose metabolism at a concentration of 10 ..mu..g/ml. However, bouvardin revealed no such antibacterial activity in these microorganisms. 8 references.
Citation Formats
Basrur, V S, Chitnis, M P, and Menon, R S.
Radiometric evaluation of antibacterial activity of bouvardin (NSC 259968) on Escherichia coli and Staphylococcus aureus.
India: N. p.,
1986.
Web.
Basrur, V S, Chitnis, M P, & Menon, R S.
Radiometric evaluation of antibacterial activity of bouvardin (NSC 259968) on Escherichia coli and Staphylococcus aureus.
India.
Basrur, V S, Chitnis, M P, and Menon, R S.
1986.
"Radiometric evaluation of antibacterial activity of bouvardin (NSC 259968) on Escherichia coli and Staphylococcus aureus."
India.
@misc{etde_6721476,
title = {Radiometric evaluation of antibacterial activity of bouvardin (NSC 259968) on Escherichia coli and Staphylococcus aureus}
author = {Basrur, V S, Chitnis, M P, and Menon, R S}
abstractNote = {Bouvardin, a cyclic hexapeptide and a new antineoplastic, protein synthesis inhibitor, was studied for its effects on bacterial growth and metabolism. E.coli and S.aureus as representative types of gram-negative and gram-positive bacteria respectively were used for these studies. Garamycin and kanamycin were also employed as known antibiotics to compare their effects with bouvardin. Both garamycin and kanamycin markedly reduced /sup 14/C-glucose metabolism at a concentration of 10 ..mu..g/ml. However, bouvardin revealed no such antibacterial activity in these microorganisms. 8 references.}
journal = []
volume = {24:3}
journal type = {AC}
place = {India}
year = {1986}
month = {Mar}
}
title = {Radiometric evaluation of antibacterial activity of bouvardin (NSC 259968) on Escherichia coli and Staphylococcus aureus}
author = {Basrur, V S, Chitnis, M P, and Menon, R S}
abstractNote = {Bouvardin, a cyclic hexapeptide and a new antineoplastic, protein synthesis inhibitor, was studied for its effects on bacterial growth and metabolism. E.coli and S.aureus as representative types of gram-negative and gram-positive bacteria respectively were used for these studies. Garamycin and kanamycin were also employed as known antibiotics to compare their effects with bouvardin. Both garamycin and kanamycin markedly reduced /sup 14/C-glucose metabolism at a concentration of 10 ..mu..g/ml. However, bouvardin revealed no such antibacterial activity in these microorganisms. 8 references.}
journal = []
volume = {24:3}
journal type = {AC}
place = {India}
year = {1986}
month = {Mar}
}