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Experimental study upon the effect of irradiation on callus formation of fracture. Observation of vascular alteration and callus formation

Abstract

Irradiation effects on callus formation after bone fracture were studied in rats with fractured right lower extremity. Follow-up study was continued for 112 days since 3000 rad was irradiated to the fractured site 3 days after bone fracture. Callus formation was noted in both of the outer and inner part (bone marrow) of the diaphysis before 14 days after bone fracture, but it was slow and sparse compared with that of non-irradiated group. Callus formation tended to disappear gradually from the outside of the diaphysis after 28 days after bone fracture. Strong disturbance was found in the surrounding vascular system at this time. Inside of the diaphysis, callus formation was restricted the end of the fracture, where lamellar calluses fused together. Changes in vascular system remained until 56 days after bone fracture. Vascular distribution was most dense 28 days after bone fracture. In many of the calluses which have established fusion, findings suggested excessive calcification in the trabeculae. Vascular distribution at this time was sparse, vascular formation was markedly suppressed in the bone marrow, and very little vascular formation was found in the fractured edges of the bone.
Authors:
Saigusa, F [1] 
  1. Nippon Dental Coll., Tokyo
Publication Date:
Feb 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-13-707838; EDB-83-019151
Resource Relation:
Journal Name: Shigaku; (Japan); Journal Volume: 68:5
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; BIOLOGICAL RECOVERY; BIOLOGICAL RADIATION EFFECTS; BONE FRACTURES; BIOMEDICAL RADIOGRAPHY; BLOOD VESSELS; BONE MARROW; GAMMA RADIATION; OSTEORADIONECROSIS; RATS; TIME DEPENDENCE; TRABECULAR BONE; ANIMAL TISSUES; ANIMALS; BIOLOGICAL EFFECTS; BODY; BONE TISSUES; CARDIOVASCULAR SYSTEM; CONNECTIVE TISSUE; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTROMAGNETIC RADIATION; HEMATOPOIETIC SYSTEM; INJURIES; IONIZING RADIATIONS; LOCAL RADIATION EFFECTS; MAMMALS; MEDICINE; NECROSIS; NUCLEAR MEDICINE; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIATION INJURIES; RADIATIONS; RADIOLOGY; RECOVERY; RODENTS; SKELETAL DISEASES; TISSUES; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
6701971
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: SHIGA
Submitting Site:
HEDB
Size:
Pages: 916-935
Announcement Date:
Oct 01, 1982

Citation Formats

Saigusa, F. Experimental study upon the effect of irradiation on callus formation of fracture. Observation of vascular alteration and callus formation. Japan: N. p., 1981. Web.
Saigusa, F. Experimental study upon the effect of irradiation on callus formation of fracture. Observation of vascular alteration and callus formation. Japan.
Saigusa, F. 1981. "Experimental study upon the effect of irradiation on callus formation of fracture. Observation of vascular alteration and callus formation." Japan.
@misc{etde_6701971,
title = {Experimental study upon the effect of irradiation on callus formation of fracture. Observation of vascular alteration and callus formation}
author = {Saigusa, F}
abstractNote = {Irradiation effects on callus formation after bone fracture were studied in rats with fractured right lower extremity. Follow-up study was continued for 112 days since 3000 rad was irradiated to the fractured site 3 days after bone fracture. Callus formation was noted in both of the outer and inner part (bone marrow) of the diaphysis before 14 days after bone fracture, but it was slow and sparse compared with that of non-irradiated group. Callus formation tended to disappear gradually from the outside of the diaphysis after 28 days after bone fracture. Strong disturbance was found in the surrounding vascular system at this time. Inside of the diaphysis, callus formation was restricted the end of the fracture, where lamellar calluses fused together. Changes in vascular system remained until 56 days after bone fracture. Vascular distribution was most dense 28 days after bone fracture. In many of the calluses which have established fusion, findings suggested excessive calcification in the trabeculae. Vascular distribution at this time was sparse, vascular formation was markedly suppressed in the bone marrow, and very little vascular formation was found in the fractured edges of the bone.}
journal = []
volume = {68:5}
journal type = {AC}
place = {Japan}
year = {1981}
month = {Feb}
}