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Liver polyribosome distribution in intact and adrenalectomized rats exposed to. gamma. radiation

Abstract

The mechanism(s) by which gamma radiation influences liver polyribosome distribution was studied in groups of intact and adrenalectomized male rats. A shift from light to heavy aggregates occurred in the polyribosomes of both intact and adrenalectomized rats after they were exposed to gamma rays. In irradiated adrenalectomized rats, however, the shift to heavier aggregates was not as great as that which occurred in irradiated adrenal-intact animals. Subcutaneous injection of cortisone acetate (10 mg/100 g body weight) also altered the liver polyribosome patterns of both intact and adrenalectomized rats within 8 hours of its administration. The shift which occurred following cortisone administration, however, was less striking than that seen after irradiation only. Thus, although adrenal glucocorticoids contribute to the radiation-indu ied shift in liver polyribosomes in adrenal-intact rats, other factors appear to be involved, since the shift is also obtained in adrenalectomized animals.
Authors:
Yatvin, M B; Abdel-Halim, M N; [1]  Wisconsin Univ., Madison (USA). Dept. of Human Oncology)
  1. Wisconsin Univ., Madison (USA). Dept. of Radiology
Publication Date:
Jun 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-09-398296; EDB-78-125693
Resource Relation:
Journal Name: Strahlentherapie; (Germany, Federal Republic of); Journal Volume: 154:6
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; ADRENALECTOMY; RADIOSENSITIVITY EFFECTS; CORTISONE; RIBOSOMES; BIOLOGICAL RADIATION EFFECTS; DISTRIBUTION; GAMMA RADIATION; INJECTION; IRRADIATION; LIVER; MALES; RATS; ADRENAL HORMONES; ANIMALS; BIOLOGICAL EFFECTS; BODY; CELL CONSTITUENTS; CORTICOSTEROIDS; DIGESTIVE SYSTEM; ELECTROMAGNETIC RADIATION; GLANDS; GLUCOCORTICOIDS; HORMONES; HYDROXY COMPOUNDS; INTAKE; IONIZING RADIATIONS; KETONES; MAMMALS; MEDICINE; ORGANIC COMPOUNDS; ORGANOIDS; ORGANS; PREGNANES; RADIATION EFFECTS; RADIATIONS; RODENTS; STEROID HORMONES; STEROIDS; SURGERY; VERTEBRATES; 560152* - Radiation Effects on Animals- Animals
OSTI ID:
6691064
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: STRAA
Submitting Site:
INIS
Size:
Pages: 419-423
Announcement Date:
Sep 01, 1978

Citation Formats

Yatvin, M B, Abdel-Halim, M N, and Wisconsin Univ., Madison (USA). Dept. of Human Oncology). Liver polyribosome distribution in intact and adrenalectomized rats exposed to. gamma. radiation. Germany: N. p., 1978. Web.
Yatvin, M B, Abdel-Halim, M N, & Wisconsin Univ., Madison (USA). Dept. of Human Oncology). Liver polyribosome distribution in intact and adrenalectomized rats exposed to. gamma. radiation. Germany.
Yatvin, M B, Abdel-Halim, M N, and Wisconsin Univ., Madison (USA). Dept. of Human Oncology). 1978. "Liver polyribosome distribution in intact and adrenalectomized rats exposed to. gamma. radiation." Germany.
@misc{etde_6691064,
title = {Liver polyribosome distribution in intact and adrenalectomized rats exposed to. gamma. radiation}
author = {Yatvin, M B, Abdel-Halim, M N, and Wisconsin Univ., Madison (USA). Dept. of Human Oncology)}
abstractNote = {The mechanism(s) by which gamma radiation influences liver polyribosome distribution was studied in groups of intact and adrenalectomized male rats. A shift from light to heavy aggregates occurred in the polyribosomes of both intact and adrenalectomized rats after they were exposed to gamma rays. In irradiated adrenalectomized rats, however, the shift to heavier aggregates was not as great as that which occurred in irradiated adrenal-intact animals. Subcutaneous injection of cortisone acetate (10 mg/100 g body weight) also altered the liver polyribosome patterns of both intact and adrenalectomized rats within 8 hours of its administration. The shift which occurred following cortisone administration, however, was less striking than that seen after irradiation only. Thus, although adrenal glucocorticoids contribute to the radiation-indu ied shift in liver polyribosomes in adrenal-intact rats, other factors appear to be involved, since the shift is also obtained in adrenalectomized animals.}
journal = []
volume = {154:6}
journal type = {AC}
place = {Germany}
year = {1978}
month = {Jun}
}