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Iminodiacetic acid derivatives of benzimidazole. Synthesis of N-(benzimidazol-2-ylmethyl)iminodiacetic acids

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Abstract

Ten new N-(2-benzimidazolylmethyl)iminodiacetic acids (BIMIDA) have been synthesized from the corresponding o-phenylenediamines via intermediate 2-chloromethyl and 2-aminomethyl benzimidazoles as ligands for Tc-99m. Anomalies associated with the synthesis of the iodo-substituted compound are described.
Authors:
Hunt, F C; Wilson, J G [1] 
  1. Australian Atomic Energy Commission Research Establishment, Lucas Heights. Isotope Div.
Publication Date:
Jan 01, 1983
Product Type:
Journal Article
Reference Number:
AIX-15-043396; EDB-84-130960
Resource Relation:
Journal Name: Aust. J. Chem.; (Australia); Journal Volume: 36:11
Subject:
37 INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; BENZIMIDAZOLES; CHEMICAL PREPARATION; RADIOPHARMACEUTICALS; TECHNETIUM 99; RADIOCHEMISTRY; DICARBOXYLIC ACIDS; LIGANDS; AZOLES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CARBOXYLIC ACIDS; CHEMISTRY; DRUGS; HETEROCYCLIC COMPOUNDS; HOURS LIVING RADIOISOTOPES; IMIDAZOLES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; RADIOISOTOPES; SYNTHESIS; TECHNETIUM ISOTOPES; YEARS LIVING RADIOISOTOPES; 400301* - Organic Chemistry- Chemical & Physicochemical Properties- (-1987); 400702 - Radiochemistry & Nuclear Chemistry- Properties of Radioactive Materials
OSTI ID:
6675172
Country of Origin:
Australia
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: AJCHA
Submitting Site:
HEDB
Size:
Pages: 2317-2325
Announcement Date:
Jul 01, 1984

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Citation Formats

Hunt, F C, and Wilson, J G. Iminodiacetic acid derivatives of benzimidazole. Synthesis of N-(benzimidazol-2-ylmethyl)iminodiacetic acids. Australia: N. p., 1983. Web.
Hunt, F C, & Wilson, J G. Iminodiacetic acid derivatives of benzimidazole. Synthesis of N-(benzimidazol-2-ylmethyl)iminodiacetic acids. Australia.
Hunt, F C, and Wilson, J G. 1983. "Iminodiacetic acid derivatives of benzimidazole. Synthesis of N-(benzimidazol-2-ylmethyl)iminodiacetic acids." Australia.
@misc{etde_6675172,
title = {Iminodiacetic acid derivatives of benzimidazole. Synthesis of N-(benzimidazol-2-ylmethyl)iminodiacetic acids}
 author = {Hunt, F C, and Wilson, J G}
 abstractNote = {Ten new N-(2-benzimidazolylmethyl)iminodiacetic acids (BIMIDA) have been synthesized from the corresponding o-phenylenediamines via intermediate 2-chloromethyl and 2-aminomethyl benzimidazoles as ligands for Tc-99m. Anomalies associated with the synthesis of the iodo-substituted compound are described.}
 journal = []
 volume = {36:11}
 journal type = {AC}
 place = {Australia}
 year = {1983}
 month = {Jan}
 }