You need JavaScript to view this

Demonstration of conjugated dopamine in monkey CSF by gas chromatography-mass spectrometry

Journal Article:

Abstract

A method for measuring unconjugated and conjugated dopamine in body tissues and fluids is described. Conjugated dopamine was hydrolyzed in acid to unconjugated dopamine, separated from the sample matrix by alumina chromatography, and assayed by gas chromatography-mass spectrometry. Conjugated dopamine was detected in greater concentrations than unconjugated dopamine in CSF taken from lateral ventricle or thecal sac of the Rhesus monkey. Haloperidol administration did not increase the levels of conjugated dopamine in lumbar CSF.
Publication Date:
Sep 01, 1982
Product Type:
Journal Article
Reference Number:
EDB-83-018632
Resource Relation:
Journal Name: J. Neurochem.; (United Kingdom); Journal Volume: 39:3
Subject:
59 BASIC BIOLOGICAL SCIENCES; CARBON ISOTOPES; ISOTOPE APPLICATIONS; DOPAMINE; MEASURING METHODS; BIOCHEMISTRY; CEREBROSPINAL FLUID; GAS CHROMATOGRAPHY; MACACUS; MASS SPECTROSCOPY; AMINES; ANIMALS; AROMATICS; AUTONOMIC NERVOUS SYSTEM AGENTS; BIOLOGICAL MATERIALS; BODY FLUIDS; CARDIOTONICS; CARDIOVASCULAR AGENTS; CHEMISTRY; CHROMATOGRAPHY; DRUGS; HYDROXY COMPOUNDS; ISOTOPES; MAMMALS; MATERIALS; MONKEYS; NEUROREGULATORS; ORGANIC COMPOUNDS; PHENOLS; POLYPHENOLS; PRIMATES; SEPARATION PROCESSES; SPECTROSCOPY; SYMPATHOMIMETICS; VERTEBRATES; 550201* - Biochemistry- Tracer Techniques
OSTI ID:
6657623
Research Organizations:
School of Veterinary Medicine, Purdue University, West Lafayette, Indiana
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JONRA
Submitting Site:
HEDB
Size:
Pages: 726-728
Announcement Date:

Journal Article:

Citation Formats

Elchisak, M A, Powers, K H, and Ebert, M H. Demonstration of conjugated dopamine in monkey CSF by gas chromatography-mass spectrometry. United Kingdom: N. p., 1982. Web.
Elchisak, M A, Powers, K H, & Ebert, M H. Demonstration of conjugated dopamine in monkey CSF by gas chromatography-mass spectrometry. United Kingdom.
Elchisak, M A, Powers, K H, and Ebert, M H. 1982. "Demonstration of conjugated dopamine in monkey CSF by gas chromatography-mass spectrometry." United Kingdom.
@misc{etde_6657623,
title = {Demonstration of conjugated dopamine in monkey CSF by gas chromatography-mass spectrometry}
author = {Elchisak, M A, Powers, K H, and Ebert, M H}
abstractNote = {A method for measuring unconjugated and conjugated dopamine in body tissues and fluids is described. Conjugated dopamine was hydrolyzed in acid to unconjugated dopamine, separated from the sample matrix by alumina chromatography, and assayed by gas chromatography-mass spectrometry. Conjugated dopamine was detected in greater concentrations than unconjugated dopamine in CSF taken from lateral ventricle or thecal sac of the Rhesus monkey. Haloperidol administration did not increase the levels of conjugated dopamine in lumbar CSF.}
journal = {J. Neurochem.; (United Kingdom)}
volume = {39:3}
journal type = {AC}
place = {United Kingdom}
year = {1982}
month = {Sep}
}