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Photochemotherapy - psoralens + UV-A(PUVA) - does it increase the risk for cancer. Fotokjemoterapi - psoralen + UV-A(PUVA) - oeket risiko for kreft

Journal Article:

Abstract

Photochemotherapy with psoralens + ultraviolet (UV)-A light (PUVA) has been used for about 16 years to treat psoriasis. Some reports have indicated a higher frequency of cutaneous squamous cell carcinoma among treated patients. The results are not consistent, however, and are not generally conceded. The material from Ullevaal Hospital comprises 585 patients who have been treated with PUVA from 1977 to 1991. Three patients developed cutaneous squamous cell carcinoma, but in one of them the tumour developed before start of PUVA treatment. The two others had received only very small doses. One of them had an intraepithelial cancer of the penis. In addition the authors registered various internal cancers in 25 patients. The Norwegian Cancer Registry compared the patient material with a matched control group as regards sex, age and age-specific incidence rate. There was no statistically significant difference in incidence between the patient and the control group. 15 refs., 1 tab.
Authors:
Harnes, D K; Thune, P [1] 
  1. Ullevaal Hospital, Oslo (Norway)
Publication Date:
Jan 01, 1993
Product Type:
Journal Article
Reference Number:
AIX-24-038313; EDB-93-066243
Resource Relation:
Journal Name: Tidsskrift for den Norske Laegeforening; (Norway); Journal Volume: 113:2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; PSORIASIS; RADIOTHERAPY; SIDE EFFECTS; CARCINOMAS; PATIENTS; PHOTOCHEMISTRY; PSORALEN; SKIN; ULTRAVIOLET RADIATION; ANTICOAGULANTS; BODY; CHEMISTRY; COUMARINS; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; HEMATOLOGIC AGENTS; HETEROCYCLIC COMPOUNDS; MEDICINE; NEOPLASMS; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; ORGANS; RADIATIONS; RADIOLOGY; SKIN DISEASES; THERAPY; 550603* - Medicine- External Radiation in Therapy- (1980-)
OSTI ID:
6614956
Country of Origin:
Norway
Language:
Norwegian
Other Identifying Numbers:
Journal ID: ISSN 0029-2001; CODEN: TNLAAH
Submitting Site:
NWN
Size:
Pages: 200-201
Announcement Date:

Journal Article:

Citation Formats

Harnes, D K, and Thune, P. Photochemotherapy - psoralens + UV-A(PUVA) - does it increase the risk for cancer. Fotokjemoterapi - psoralen + UV-A(PUVA) - oeket risiko for kreft. Norway: N. p., 1993. Web.
Harnes, D K, & Thune, P. Photochemotherapy - psoralens + UV-A(PUVA) - does it increase the risk for cancer. Fotokjemoterapi - psoralen + UV-A(PUVA) - oeket risiko for kreft. Norway.
Harnes, D K, and Thune, P. 1993. "Photochemotherapy - psoralens + UV-A(PUVA) - does it increase the risk for cancer. Fotokjemoterapi - psoralen + UV-A(PUVA) - oeket risiko for kreft." Norway.
@misc{etde_6614956,
title = {Photochemotherapy - psoralens + UV-A(PUVA) - does it increase the risk for cancer. Fotokjemoterapi - psoralen + UV-A(PUVA) - oeket risiko for kreft}
author = {Harnes, D K, and Thune, P}
abstractNote = {Photochemotherapy with psoralens + ultraviolet (UV)-A light (PUVA) has been used for about 16 years to treat psoriasis. Some reports have indicated a higher frequency of cutaneous squamous cell carcinoma among treated patients. The results are not consistent, however, and are not generally conceded. The material from Ullevaal Hospital comprises 585 patients who have been treated with PUVA from 1977 to 1991. Three patients developed cutaneous squamous cell carcinoma, but in one of them the tumour developed before start of PUVA treatment. The two others had received only very small doses. One of them had an intraepithelial cancer of the penis. In addition the authors registered various internal cancers in 25 patients. The Norwegian Cancer Registry compared the patient material with a matched control group as regards sex, age and age-specific incidence rate. There was no statistically significant difference in incidence between the patient and the control group. 15 refs., 1 tab.}
journal = {Tidsskrift for den Norske Laegeforening; (Norway)}
volume = {113:2}
journal type = {AC}
place = {Norway}
year = {1993}
month = {Jan}
}