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Use of radioisotope techniques for the diagnosis of obstructive airway disease

Abstract

Perfusion scintigraphy, radioaerosol inhalation scintigraphy, /sup 133/Xe studies and sup(81m)Kr studies are useful radioisotope techniques for the detection of regional pulmonary abnormalities in obstructive airway disease. The patient during asthmatic attack shows the perfusion defects with indefinite boundary, which may change during the following several days. Decreased ventilation are seen on the regions with perfusion defects, and ventilatory defects are more marked than those of perfusion. On the other hand, these abnomal findings are reversible. In chronic emphysema or chronic bronchitis, the regions with decreased perfusion usually cannot be correlated with any specific segments, and scintigraphys done repeatedly fail to show re-vascularization on the regions. In the radioaerosol inhalation scintigraphy, deposition pattern reveal the severity of COPD. In addition, xenon studies in the diseases show marked or moderate prolongation of wash-out from the abnormal region, and the abnormalities of ventilation are equal to or exceed the abnormalities of perfusion.
Authors:
Furudate, M; Itoh, K; Shida, A; Minami, Y [1] 
  1. Hokkaido Univ., Sapporo (Japan). School of Medicine
Publication Date:
Jul 01, 1981
Product Type:
Journal Article
Reference Number:
AIX-13-703090; EDB-83-027610
Resource Relation:
Journal Name: Rinsho Hoshasen; (Japan); Journal Volume: 26:7
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ASTHMA; DIAGNOSIS; BRONCHITIS; EMPHYSEMA; KRYPTON 81; DIAGNOSTIC USES; LUNGS; SCINTISCANNING; XENON 133; BIOLOGICAL FUNCTIONS; BLOOD FLOW; INHALATION; PERFUSED ORGANS; RADIOACTIVE AEROSOLS; RADIOPHARMACEUTICALS; TECHNETIUM 99; AEROSOLS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COLLOIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; DISPERSIONS; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; FUNCTIONS; HOURS LIVING RADIOISOTOPES; INTAKE; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; KRYPTON ISOTOPES; LABELLED COMPOUNDS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; RESPIRATORY SYSTEM DISEASES; SECONDS LIVING RADIOISOTOPES; SOLS; TECHNETIUM ISOTOPES; USES; XENON ISOTOPES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6606365
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: RHOSA
Submitting Site:
HEDB
Size:
Pages: 727-732
Announcement Date:
Sep 01, 1982

Citation Formats

Furudate, M, Itoh, K, Shida, A, and Minami, Y. Use of radioisotope techniques for the diagnosis of obstructive airway disease. Japan: N. p., 1981. Web.
Furudate, M, Itoh, K, Shida, A, & Minami, Y. Use of radioisotope techniques for the diagnosis of obstructive airway disease. Japan.
Furudate, M, Itoh, K, Shida, A, and Minami, Y. 1981. "Use of radioisotope techniques for the diagnosis of obstructive airway disease." Japan.
@misc{etde_6606365,
title = {Use of radioisotope techniques for the diagnosis of obstructive airway disease}
author = {Furudate, M, Itoh, K, Shida, A, and Minami, Y}
abstractNote = {Perfusion scintigraphy, radioaerosol inhalation scintigraphy, /sup 133/Xe studies and sup(81m)Kr studies are useful radioisotope techniques for the detection of regional pulmonary abnormalities in obstructive airway disease. The patient during asthmatic attack shows the perfusion defects with indefinite boundary, which may change during the following several days. Decreased ventilation are seen on the regions with perfusion defects, and ventilatory defects are more marked than those of perfusion. On the other hand, these abnomal findings are reversible. In chronic emphysema or chronic bronchitis, the regions with decreased perfusion usually cannot be correlated with any specific segments, and scintigraphys done repeatedly fail to show re-vascularization on the regions. In the radioaerosol inhalation scintigraphy, deposition pattern reveal the severity of COPD. In addition, xenon studies in the diseases show marked or moderate prolongation of wash-out from the abnormal region, and the abnormalities of ventilation are equal to or exceed the abnormalities of perfusion.}
journal = []
volume = {26:7}
journal type = {AC}
place = {Japan}
year = {1981}
month = {Jul}
}