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Effect of radiation and combined chemoradiation therapy on cardiac activity in patients with esophagus cancer. [Combined effects of /sup 60/Co. gamma. rays and methylglyoxal-bis(guanylhydrazone) an antineoplastic drug]

Abstract

The results of a comparative study of the effect of radiation and combined chemoradiation therapy with methyl-GAG in 51 patients with cancer of the chest region of the esophagus indicate an adverse effect of these methods of treatment on cardiac activity. Against the background of chemoradiation therapy, these changes were more marked due perhaps to some cardiotoxic effect of methyl-GAG. However, the changes induced did not lead to considerable disorders of hemodynamics during treatment.
Publication Date:
Dec 01, 1978
Product Type:
Journal Article
Reference Number:
EDB-79-027786
Resource Relation:
Journal Name: Med. Radiol.; (USSR); Journal Volume: 23:12
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 62 RADIOLOGY AND NUCLEAR MEDICINE; ANTINEOPLASTIC DRUGS; BIOLOGICAL EFFECTS; BIOLOGICAL FUNCTIONS; PATHOLOGICAL CHANGES; CHEMOTHERAPY; SIDE EFFECTS; HEART; DELAYED RADIATION EFFECTS; RADIOTHERAPY; COBALT 60; ESOPHAGUS; GAMMA RADIATION; LOCAL IRRADIATION; NEOPLASMS; PATIENTS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL RADIATION EFFECTS; BODY; CARDIOVASCULAR SYSTEM; COBALT ISOTOPES; DIGESTIVE SYSTEM; DISEASES; DRUGS; ELECTROMAGNETIC RADIATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MEDICINE; MINUTES LIVING RADIOISOTOPES; NUCLEAR MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; THERAPY; YEARS LIVING RADIOISOTOPES; 560151* - Radiation Effects on Animals- Man; 550600 - Medicine
OSTI ID:
6591837
Research Organizations:
Oncology Scientific Center, Moscow, USSR
Country of Origin:
USSR
Language:
Russian
Other Identifying Numbers:
Journal ID: CODEN: MERAA
Submitting Site:
TIC
Size:
Pages: 55-60
Announcement Date:
Feb 01, 1979

Citation Formats

Neklyudova, V I, Shkhvatsabaya, L V, and Ivanova, E M. Effect of radiation and combined chemoradiation therapy on cardiac activity in patients with esophagus cancer. [Combined effects of /sup 60/Co. gamma. rays and methylglyoxal-bis(guanylhydrazone) an antineoplastic drug]. USSR: N. p., 1978. Web.
Neklyudova, V I, Shkhvatsabaya, L V, & Ivanova, E M. Effect of radiation and combined chemoradiation therapy on cardiac activity in patients with esophagus cancer. [Combined effects of /sup 60/Co. gamma. rays and methylglyoxal-bis(guanylhydrazone) an antineoplastic drug]. USSR.
Neklyudova, V I, Shkhvatsabaya, L V, and Ivanova, E M. 1978. "Effect of radiation and combined chemoradiation therapy on cardiac activity in patients with esophagus cancer. [Combined effects of /sup 60/Co. gamma. rays and methylglyoxal-bis(guanylhydrazone) an antineoplastic drug]." USSR.
@misc{etde_6591837,
title = {Effect of radiation and combined chemoradiation therapy on cardiac activity in patients with esophagus cancer. [Combined effects of /sup 60/Co. gamma. rays and methylglyoxal-bis(guanylhydrazone) an antineoplastic drug]}
author = {Neklyudova, V I, Shkhvatsabaya, L V, and Ivanova, E M}
abstractNote = {The results of a comparative study of the effect of radiation and combined chemoradiation therapy with methyl-GAG in 51 patients with cancer of the chest region of the esophagus indicate an adverse effect of these methods of treatment on cardiac activity. Against the background of chemoradiation therapy, these changes were more marked due perhaps to some cardiotoxic effect of methyl-GAG. However, the changes induced did not lead to considerable disorders of hemodynamics during treatment.}
journal = []
volume = {23:12}
journal type = {AC}
place = {USSR}
year = {1978}
month = {Dec}
}