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Evaluation of supra- and infratentorial brain atrophy by computerized tomography in spinocerebellar degeneration

Journal Article:

Abstract

Measurement of various parameters of supra- and infratentorial brain atrophy in computerized tomographs of 142 cases of spinocerebellar degeneration (SCD) and 100 age and sex matched controls was carried out in order to investigate whether these parameters would correspond to the subtypes of this disease and differing grades of various clinical manifestations. One supra- and all infratentorial parameters of SCD showed statistically significant atrophy with a risk of P < 0.005. Among the subtypes, OPCA had a more severely atrophied pons than LCCA (P < 0.005), Menzel (P < 0.05) and SSP (P < 0.01). There was a correlation between the distribution of symptoms like gait, speech, ataxia of extremities and ocular movement disorders, and distribution and degree of infratentorial atrophy with statistical significance (P < 0.05 -- P < 0.005). The degree of atrophy of the pons and the width of the IV ventricle were directly proportional to the duration of the illness in cases of less than 10 years, but not to those of over 10 years. Follow-up CT scan was done for 24 patients, 12 within 3 years, 12 after the lapse of 3 years. The latter group showed statistically significant atrophy between the 1st and 2nd  More>>
Publication Date:
Aug 01, 1986
Product Type:
Journal Article
Reference Number:
AIX-18-051451; EDB-87-089772
Resource Relation:
Journal Name: Jpn. J. Med.; (Japan); Journal Volume: 25:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; HEAD; CAT SCANNING; ATROPHY; CEREBELLUM; IMAGES; NERVOUS SYSTEM DISEASES; PATIENTS; SPINAL CORD; BODY; BODY AREAS; BRAIN; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; NERVOUS SYSTEM; ORGANS; PATHOLOGICAL CHANGES; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6590066
Research Organizations:
Fujita-Gakuen Health Univ., Toyoake, Aichi, Japan
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JJMDA
Submitting Site:
INIS
Size:
Pages: 238-245
Announcement Date:

Journal Article:

Citation Formats

Yamamoto, Hiroko, Asano, Yasuhiko, Watanabe, Takatoshi, Hirao, Yoshitaka, Mizuno, Yasushi, and Sobue, Itsuro. Evaluation of supra- and infratentorial brain atrophy by computerized tomography in spinocerebellar degeneration. Japan: N. p., 1986. Web.
Yamamoto, Hiroko, Asano, Yasuhiko, Watanabe, Takatoshi, Hirao, Yoshitaka, Mizuno, Yasushi, & Sobue, Itsuro. Evaluation of supra- and infratentorial brain atrophy by computerized tomography in spinocerebellar degeneration. Japan.
Yamamoto, Hiroko, Asano, Yasuhiko, Watanabe, Takatoshi, Hirao, Yoshitaka, Mizuno, Yasushi, and Sobue, Itsuro. 1986. "Evaluation of supra- and infratentorial brain atrophy by computerized tomography in spinocerebellar degeneration." Japan.
@misc{etde_6590066,
title = {Evaluation of supra- and infratentorial brain atrophy by computerized tomography in spinocerebellar degeneration}
author = {Yamamoto, Hiroko, Asano, Yasuhiko, Watanabe, Takatoshi, Hirao, Yoshitaka, Mizuno, Yasushi, and Sobue, Itsuro}
abstractNote = {Measurement of various parameters of supra- and infratentorial brain atrophy in computerized tomographs of 142 cases of spinocerebellar degeneration (SCD) and 100 age and sex matched controls was carried out in order to investigate whether these parameters would correspond to the subtypes of this disease and differing grades of various clinical manifestations. One supra- and all infratentorial parameters of SCD showed statistically significant atrophy with a risk of P < 0.005. Among the subtypes, OPCA had a more severely atrophied pons than LCCA (P < 0.005), Menzel (P < 0.05) and SSP (P < 0.01). There was a correlation between the distribution of symptoms like gait, speech, ataxia of extremities and ocular movement disorders, and distribution and degree of infratentorial atrophy with statistical significance (P < 0.05 -- P < 0.005). The degree of atrophy of the pons and the width of the IV ventricle were directly proportional to the duration of the illness in cases of less than 10 years, but not to those of over 10 years. Follow-up CT scan was done for 24 patients, 12 within 3 years, 12 after the lapse of 3 years. The latter group showed statistically significant atrophy between the 1st and 2nd scans in several parameters, but there was no significance between those of the former group.}
journal = {Jpn. J. Med.; (Japan)}
volume = {25:3}
journal type = {AC}
place = {Japan}
year = {1986}
month = {Aug}
}