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Radioimmunoassay - a revolution in analysis

Abstract

The RIA is an analytical method where the sensitivity of radioactive measurements is coupled with the specificity of the antigen-antibody reaction. Substances down to a picogram concentration per ml serum (or biological material) can be measured in the presence of otherwise interfering substances in concentrations a few million times higher. The method is easy to carry out (test tube chemistry). The main field of application at the moment is endocrinology; further applications are in pharmaceutical research, environmental protection, forensic medicine, and general analytics. Radioactivity is only used in vitro, in nanocurie amounts, so that radiation exposure is negligible.
Authors:
Strecker, H; Eckert, H G [1] 
  1. Farbwerke Hoechst A.G., Frankfurt am Main (Germany, F.R.). Radiochemisches Lab.
Publication Date:
Apr 01, 1978
Product Type:
Journal Article
Reference Number:
AIX-09-398482; EDB-79-014506
Resource Relation:
Journal Name: GIT Labor-Med.; (Germany, Federal Republic of); Journal Volume: 2
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CRIME DETECTION; RADIOIMMUNOASSAY; DRUGS; ENZYMES; HORMONES; NUCLEAR MEDICINE; DIAGNOSTIC USES; REVIEWS; VITAMINS; AMP; ANTIGEN-ANTIBODY REACTIONS; COMPARATIVE EVALUATIONS; DNA; FERRITIN; IMMUNOGLOBULINS; IODINE 125; LABELLING; LYMPHOCYTES; RADIOACTIVITY; TSH; ANIMAL CELLS; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY FLUIDS; COMPLEXES; CONNECTIVE TISSUE CELLS; DAYS LIVING RADIOISOTOPES; DOCUMENT TYPES; ELECTRON CAPTURE RADIOISOTOPES; GLOBULINS; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; IRON COMPLEXES; ISOTOPE APPLICATIONS; ISOTOPES; LEUKOCYTES; MEDICINE; NUCLEI; NUCLEIC ACIDS; NUCLEOTIDES; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PITUITARY HORMONES; PROTEINS; RADIOASSAY; RADIOISOTOPES; SOMATIC CELLS; TRACER TECHNIQUES; TRANSITION ELEMENT COMPLEXES; USES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6589812
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: GLMDD
Submitting Site:
INIS
Size:
Pages: 106-116
Announcement Date:
Sep 01, 1978

Citation Formats

Strecker, H, and Eckert, H G. Radioimmunoassay - a revolution in analysis. Germany: N. p., 1978. Web.
Strecker, H, & Eckert, H G. Radioimmunoassay - a revolution in analysis. Germany.
Strecker, H, and Eckert, H G. 1978. "Radioimmunoassay - a revolution in analysis." Germany.
@misc{etde_6589812,
title = {Radioimmunoassay - a revolution in analysis}
author = {Strecker, H, and Eckert, H G}
abstractNote = {The RIA is an analytical method where the sensitivity of radioactive measurements is coupled with the specificity of the antigen-antibody reaction. Substances down to a picogram concentration per ml serum (or biological material) can be measured in the presence of otherwise interfering substances in concentrations a few million times higher. The method is easy to carry out (test tube chemistry). The main field of application at the moment is endocrinology; further applications are in pharmaceutical research, environmental protection, forensic medicine, and general analytics. Radioactivity is only used in vitro, in nanocurie amounts, so that radiation exposure is negligible.}
journal = []
volume = {2}
journal type = {AC}
place = {Germany}
year = {1978}
month = {Apr}
}