Abstract
When the radiosensitivity in N/sub 2/O suspension was compared with that in N/sub 2/ suspension, the dose modifying factors of N/sub 2/O on Micrococcus radiodurans R/sub 1/, Pseudomonas radiora 0-1, M. lysodeikticus and Bacillus pumilus E601 were 3.7, 2.9, 2.4 and 1.7, respectively. The sensitizing action of N/sub 2/O was diminished by ethanol as OH radical scavenger. This sensitization was further prevented by catalase and peroxidase. However, thermally inactivated catalase was without effect. In addition, the number of viable cells did not change in 0.1 mM H/sub 2/O/sub 2/ at 0/sup 0/C. These results indicate that N/sub 2/O sensitization is due to the cooperative action of OH radicals and H/sub 2/O/sub 2/, and that it would allow H/sub 2/O/sub 2/ to sensitize only when OH radicals were present.
Citation Formats
Watanabe, H, Iizuka, H, and Takehisa, M.
Evidence that nitrous oxide enhances the radiosensitivity of bacterial vegetative cells by the co-operative action of the hydroxyl radical and hydrogen peroxide.
Germany: N. p.,
1980.
Web.
doi:10.1002/jobm.3630200810.
Watanabe, H, Iizuka, H, & Takehisa, M.
Evidence that nitrous oxide enhances the radiosensitivity of bacterial vegetative cells by the co-operative action of the hydroxyl radical and hydrogen peroxide.
Germany.
https://doi.org/10.1002/jobm.3630200810
Watanabe, H, Iizuka, H, and Takehisa, M.
1980.
"Evidence that nitrous oxide enhances the radiosensitivity of bacterial vegetative cells by the co-operative action of the hydroxyl radical and hydrogen peroxide."
Germany.
https://doi.org/10.1002/jobm.3630200810.
@misc{etde_6581013,
title = {Evidence that nitrous oxide enhances the radiosensitivity of bacterial vegetative cells by the co-operative action of the hydroxyl radical and hydrogen peroxide}
author = {Watanabe, H, Iizuka, H, and Takehisa, M}
abstractNote = {When the radiosensitivity in N/sub 2/O suspension was compared with that in N/sub 2/ suspension, the dose modifying factors of N/sub 2/O on Micrococcus radiodurans R/sub 1/, Pseudomonas radiora 0-1, M. lysodeikticus and Bacillus pumilus E601 were 3.7, 2.9, 2.4 and 1.7, respectively. The sensitizing action of N/sub 2/O was diminished by ethanol as OH radical scavenger. This sensitization was further prevented by catalase and peroxidase. However, thermally inactivated catalase was without effect. In addition, the number of viable cells did not change in 0.1 mM H/sub 2/O/sub 2/ at 0/sup 0/C. These results indicate that N/sub 2/O sensitization is due to the cooperative action of OH radicals and H/sub 2/O/sub 2/, and that it would allow H/sub 2/O/sub 2/ to sensitize only when OH radicals were present.}
doi = {10.1002/jobm.3630200810}
journal = []
volume = {20:8}
journal type = {AC}
place = {Germany}
year = {1980}
month = {Aug}
}
title = {Evidence that nitrous oxide enhances the radiosensitivity of bacterial vegetative cells by the co-operative action of the hydroxyl radical and hydrogen peroxide}
author = {Watanabe, H, Iizuka, H, and Takehisa, M}
abstractNote = {When the radiosensitivity in N/sub 2/O suspension was compared with that in N/sub 2/ suspension, the dose modifying factors of N/sub 2/O on Micrococcus radiodurans R/sub 1/, Pseudomonas radiora 0-1, M. lysodeikticus and Bacillus pumilus E601 were 3.7, 2.9, 2.4 and 1.7, respectively. The sensitizing action of N/sub 2/O was diminished by ethanol as OH radical scavenger. This sensitization was further prevented by catalase and peroxidase. However, thermally inactivated catalase was without effect. In addition, the number of viable cells did not change in 0.1 mM H/sub 2/O/sub 2/ at 0/sup 0/C. These results indicate that N/sub 2/O sensitization is due to the cooperative action of OH radicals and H/sub 2/O/sub 2/, and that it would allow H/sub 2/O/sub 2/ to sensitize only when OH radicals were present.}
doi = {10.1002/jobm.3630200810}
journal = []
volume = {20:8}
journal type = {AC}
place = {Germany}
year = {1980}
month = {Aug}
}