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Multigated radionuclide study of the total artificial heart

Abstract

A permanent total artificial heart, the Jarvik-7, was implanted into a 61-year-old male with a severe cardiomyopathy. Gated radionuclide studies were performed in the patient both prior to surgery and following implantation. Preoperative gated radionuclide cardiac studies revealed marked left ventricular enlargement, severe hypokinesis and a left ventricular ejection fraction of 10%. The right ventricle was moderately enlarged with a 27% ejection fraction. Following implantation of the Jarvik-7 artificial heart, gated cardiac studies were performed with a computer gated by a signal from the heart controller. The left ventricular ejection fraction was 69% and the right ventricular ejection fraction was 62%. This compared to a theoretical ejection fraction of 74% for each ventricle based on chamber anatomy. There was excellent ventricular emptying. Phase analysis showed uniform diaphragm motion. The use of gated cardiac studies in humans may prove helpful in evaluating mechanical problems with the artificial heart, such as manlfunction of the diaphragm, before they become clinically apparent.
Publication Date:
Jul 01, 1987
Product Type:
Journal Article
Reference Number:
DEN-87-009756; EDB-87-112148
Resource Relation:
Journal Name: Eur. J. Nucl. Med.; (Germany, Federal Republic of); Journal Volume: 13:4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; ARTIFICIAL ORGANS; DYNAMIC FUNCTION STUDIES; BIOMEDICAL RADIOGRAPHY; HEART; IMAGE PROCESSING; IMAGES; IMPLANTS; ISOMERIC NUCLEI; MECHANICAL PROPERTIES; PATIENTS; PERTECHNETATES; RADIOPHARMACEUTICALS; SURGERY; TECHNETIUM 99; X-RAY RADIOGRAPHY; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; DIAGNOSTIC TECHNIQUES; DRUGS; HOURS LIVING RADIOISOTOPES; INDUSTRIAL RADIOGRAPHY; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MEDICINE; NUCLEAR MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANS; OXYGEN COMPOUNDS; PROCESSING; RADIOISOTOPES; RADIOLOGY; REFRACTORY METAL COMPOUNDS; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPOUNDS; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6500912
Research Organizations:
Utah Univ., Salt Lake City, USA. Health Sciences Center
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: EJNMD
Submitting Site:
DEN
Size:
Pages: 167-170
Announcement Date:
Jul 01, 1987

Citation Formats

Datz, F L, Christian, P E, Taylor, A Jr, Hastings, W L, and De Vries, W C. Multigated radionuclide study of the total artificial heart. Germany: N. p., 1987. Web.
Datz, F L, Christian, P E, Taylor, A Jr, Hastings, W L, & De Vries, W C. Multigated radionuclide study of the total artificial heart. Germany.
Datz, F L, Christian, P E, Taylor, A Jr, Hastings, W L, and De Vries, W C. 1987. "Multigated radionuclide study of the total artificial heart." Germany.
@misc{etde_6500912,
title = {Multigated radionuclide study of the total artificial heart}
author = {Datz, F L, Christian, P E, Taylor, A Jr, Hastings, W L, and De Vries, W C}
abstractNote = {A permanent total artificial heart, the Jarvik-7, was implanted into a 61-year-old male with a severe cardiomyopathy. Gated radionuclide studies were performed in the patient both prior to surgery and following implantation. Preoperative gated radionuclide cardiac studies revealed marked left ventricular enlargement, severe hypokinesis and a left ventricular ejection fraction of 10%. The right ventricle was moderately enlarged with a 27% ejection fraction. Following implantation of the Jarvik-7 artificial heart, gated cardiac studies were performed with a computer gated by a signal from the heart controller. The left ventricular ejection fraction was 69% and the right ventricular ejection fraction was 62%. This compared to a theoretical ejection fraction of 74% for each ventricle based on chamber anatomy. There was excellent ventricular emptying. Phase analysis showed uniform diaphragm motion. The use of gated cardiac studies in humans may prove helpful in evaluating mechanical problems with the artificial heart, such as manlfunction of the diaphragm, before they become clinically apparent.}
journal = []
volume = {13:4}
journal type = {AC}
place = {Germany}
year = {1987}
month = {Jul}
}