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Basal ganglia calcification on computed tomography in systemic lupus erythematosus

Journal Article:

Abstract

The development of basal ganglia calcification was studied in 85 patients with systemic lupus erythematosus (SLE) by computed tomography (CT). Bilateral calcification of the basal ganglia was found to occur in 5 patients (5.9 %) with SLE, but was not seen in patients with rheumatoid arthritis and progressive systemic sclerosis. All were female with a mean age of 42 years (range 29 - 49). The patients with calcification of the basal ganglia had neurological symptoms, such as psychiatric problems (3 cases), grand mal seizures (1 case), CSF abnormalities (2 cases), and EEG changes (4 cases). There were significantly higher incidences of alopecia, cutaneous vasculitis, leukopenia, and thrombocytopenia in the group with calcifications than those in the group with normal CT findings. Circulating immune complexes were detected and LE tests were positive in 2 patients. Endocrinological examination showed no abnormality in any. We suggest that basal ganglia calcification in SLE might be related to cerebral vasculitis.
Publication Date:
Sep 01, 1988
Product Type:
Journal Article
Reference Number:
JPN-89-005147; EDB-89-049575
Resource Relation:
Journal Name: Yokohama Med. Bull.; (Japan); Journal Volume: 39:3-4
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBRUM; CAT SCANNING; CALCIUM COMPOUNDS; IMAGES; IMMUNITY; METABOLIC DISEASES; PATIENTS; SKIN DISEASES; ALKALINE EARTH METAL COMPOUNDS; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DISEASES; NERVOUS SYSTEM; ORGANS; TOMOGRAPHY; 550602* - Medicine- External Radiation in Diagnostics- (1980-)
OSTI ID:
6465295
Research Organizations:
Yokohama City Univ. (Japan). Faculty of Medicine
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: YMBUA
Submitting Site:
JPN
Size:
Pages: 57-65
Announcement Date:

Journal Article:

Citation Formats

Nagaoka, Shohei, Tani, Kenji, and Ishigatsubo, Yoshiaki and others. Basal ganglia calcification on computed tomography in systemic lupus erythematosus. Japan: N. p., 1988. Web.
Nagaoka, Shohei, Tani, Kenji, & Ishigatsubo, Yoshiaki and others. Basal ganglia calcification on computed tomography in systemic lupus erythematosus. Japan.
Nagaoka, Shohei, Tani, Kenji, and Ishigatsubo, Yoshiaki and others. 1988. "Basal ganglia calcification on computed tomography in systemic lupus erythematosus." Japan.
@misc{etde_6465295,
title = {Basal ganglia calcification on computed tomography in systemic lupus erythematosus}
author = {Nagaoka, Shohei, Tani, Kenji, and Ishigatsubo, Yoshiaki and others}
abstractNote = {The development of basal ganglia calcification was studied in 85 patients with systemic lupus erythematosus (SLE) by computed tomography (CT). Bilateral calcification of the basal ganglia was found to occur in 5 patients (5.9 %) with SLE, but was not seen in patients with rheumatoid arthritis and progressive systemic sclerosis. All were female with a mean age of 42 years (range 29 - 49). The patients with calcification of the basal ganglia had neurological symptoms, such as psychiatric problems (3 cases), grand mal seizures (1 case), CSF abnormalities (2 cases), and EEG changes (4 cases). There were significantly higher incidences of alopecia, cutaneous vasculitis, leukopenia, and thrombocytopenia in the group with calcifications than those in the group with normal CT findings. Circulating immune complexes were detected and LE tests were positive in 2 patients. Endocrinological examination showed no abnormality in any. We suggest that basal ganglia calcification in SLE might be related to cerebral vasculitis.}
journal = {Yokohama Med. Bull.; (Japan)}
volume = {39:3-4}
journal type = {AC}
place = {Japan}
year = {1988}
month = {Sep}
}