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Scintigraphy of liver and spleen in vinyl chloride workers

Journal Article:

Abstract

In 152 VC-exposed workers of whom 124 were employed in the PVC-production and 28 in VC-processing plants, liver and spleen imaging was performed using sup(99m)Tc-sulphur colloid and /sup 197/Hg-BMHP. In 101 (= 81%) of the 124 workers of the PVC-production plant and in 18 (= 64%) workers of PVC-processing factories pathological liver and spleen scintigrams were found. The most frequent pathological change in the scintigraphic image was an increase in splenic colloid accumulation, when compared with the liver uptake. Three angiosarcomas of the liver were detected through circumscribed defects of colloid accumulation. Sequential liver scintigraphy was done in 15 cases. In 7 patients with esophageal varices, considerable decrease in portal venous blood flow was demonstrated. - As a result of our investigations it can be stated that scintigraphically detectable changes are sensitive indicators of VC-induced lesions of the liver including liver fibrosis, portal hypertension and angiosarcoma.
Publication Date:
Oct 01, 1977
Product Type:
Journal Article
Reference Number:
AIX-09-414629; EDB-79-065012
Resource Relation:
Journal Name: Acta Hepato-Gastroenterol.; (Germany, Federal Republic of); Journal Volume: 24:5
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; DIGESTIVE SYSTEM DISEASES; DIAGNOSIS; FIBROSIS; HYPERTENSION; LIVER; SCINTISCANNING; MERCURY 197; PERSONNEL; OCCUPATIONAL DISEASES; POLYVINYLS; BIOLOGICAL EFFECTS; SARCOMAS; SPLEEN; TECHNETIUM 99; IMAGES; PATIENTS; PERFUSED ORGANS; RADIOCOLLOIDS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR DISEASES; COLLOIDS; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; DISPERSIONS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; GLANDS; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MERCURY ISOTOPES; NEOPLASMS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC POLYMERS; ORGANS; PATHOLOGICAL CHANGES; POLYMERS; RADIOISOTOPE SCANNING; RADIOISOTOPES; SYMPTOMS; TECHNETIUM ISOTOPES; VASCULAR DISEASES; YEARS LIVING RADIOISOTOPES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics; 550901 - Pathology- Tracer Techniques
OSTI ID:
6425443
Country of Origin:
Germany
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: AHGSB
Submitting Site:
INIS
Size:
Pages: 356-361
Announcement Date:

Journal Article:

Citation Formats

Biersack, H J, San Luis, T Jr, Lange, C E, Thelen, M, Veltman, G, Winkler, C, Bonn Univ. (Germany, F.R.). Klinik und Poliklinik der Haut- und Geschlechtskrankheiten, and Bonn Univ. (Germany, F.R.). Radiologische Klinik). Scintigraphy of liver and spleen in vinyl chloride workers. Germany: N. p., 1977. Web.
Biersack, H J, San Luis, T Jr, Lange, C E, Thelen, M, Veltman, G, Winkler, C, Bonn Univ. (Germany, F.R.). Klinik und Poliklinik der Haut- und Geschlechtskrankheiten, & Bonn Univ. (Germany, F.R.). Radiologische Klinik). Scintigraphy of liver and spleen in vinyl chloride workers. Germany.
Biersack, H J, San Luis, T Jr, Lange, C E, Thelen, M, Veltman, G, Winkler, C, Bonn Univ. (Germany, F.R.). Klinik und Poliklinik der Haut- und Geschlechtskrankheiten, and Bonn Univ. (Germany, F.R.). Radiologische Klinik). 1977. "Scintigraphy of liver and spleen in vinyl chloride workers." Germany.
@misc{etde_6425443,
title = {Scintigraphy of liver and spleen in vinyl chloride workers}
author = {Biersack, H J, San Luis, T Jr, Lange, C E, Thelen, M, Veltman, G, Winkler, C, Bonn Univ. (Germany, F.R.). Klinik und Poliklinik der Haut- und Geschlechtskrankheiten, and Bonn Univ. (Germany, F.R.). Radiologische Klinik)}
abstractNote = {In 152 VC-exposed workers of whom 124 were employed in the PVC-production and 28 in VC-processing plants, liver and spleen imaging was performed using sup(99m)Tc-sulphur colloid and /sup 197/Hg-BMHP. In 101 (= 81%) of the 124 workers of the PVC-production plant and in 18 (= 64%) workers of PVC-processing factories pathological liver and spleen scintigrams were found. The most frequent pathological change in the scintigraphic image was an increase in splenic colloid accumulation, when compared with the liver uptake. Three angiosarcomas of the liver were detected through circumscribed defects of colloid accumulation. Sequential liver scintigraphy was done in 15 cases. In 7 patients with esophageal varices, considerable decrease in portal venous blood flow was demonstrated. - As a result of our investigations it can be stated that scintigraphically detectable changes are sensitive indicators of VC-induced lesions of the liver including liver fibrosis, portal hypertension and angiosarcoma.}
journal = {Acta Hepato-Gastroenterol.; (Germany, Federal Republic of)}
volume = {24:5}
journal type = {AC}
place = {Germany}
year = {1977}
month = {Oct}
}