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Serum thymidine kinase activity of various cancer and HBV positive liver diseases

Journal Article:

Abstract

Clinical utility of determination of serum deoxythymidine kinase (TK) activity is described. It is well known that elevated TK level is observed in leukemia and other malignant diseases, or some viral infectious diseases. The TK activity was assayed on normal subjects, hepatitis B virus (HBV) positive liver diseases and various cancer by a newly developed high sensitive method, radioenzyme assay (REA) utilizing /sup 125/I-iododeoxyuridine as the substrate. Measurement of TK activity by the REA is revealed to be useful for ''the marker of DNA metabolism anomaly'' in leukemia, etc.
Publication Date:
Mar 01, 1987
Product Type:
Journal Article
Reference Number:
JPN-87-058050; EDB-87-134807
Resource Relation:
Journal Name: Radioisotopes (Tokyo); (Japan); Journal Volume: 36:3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; PHOSPHOTRANSFERASES; BLOOD CHEMISTRY; RADIOENZYMATIC ASSAY; DIAGNOSTIC USES; THYMIDINE; BLOOD; ENZYME ACTIVITY; HEPATITIS; IODINE 125; IODODEOXYURIDINE; LABELLED COMPOUNDS; NEOPLASMS; PATHOLOGICAL CHANGES; ANTIMETABOLITES; AZINES; BETA DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BODY FLUIDS; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM DISEASES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; ENZYMES; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; IODOURACILS; ISOTOPES; MATERIALS; NUCLEI; NUCLEOSIDES; NUCLEOTIDES; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOSPHORUS-GROUP TRANSFERASES; PYRIMIDINES; RADIOISOTOPES; RIBOSIDES; TRANSFERASES; URACILS; USES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6414945
Research Organizations:
Wakayama Medical Coll., Japan
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: RAISA
Submitting Site:
HEDB
Size:
Pages: 133-136
Announcement Date:

Journal Article:

Citation Formats

Torizumi, Kazutami, Aibata, Hirofumi, Kiji, Shigeyuki, Ohta, Kiichiro, Okamoto, Yukiharu, Ohshiro, Iwao, and Hirose, Tetsuhito. Serum thymidine kinase activity of various cancer and HBV positive liver diseases. Japan: N. p., 1987. Web.
Torizumi, Kazutami, Aibata, Hirofumi, Kiji, Shigeyuki, Ohta, Kiichiro, Okamoto, Yukiharu, Ohshiro, Iwao, & Hirose, Tetsuhito. Serum thymidine kinase activity of various cancer and HBV positive liver diseases. Japan.
Torizumi, Kazutami, Aibata, Hirofumi, Kiji, Shigeyuki, Ohta, Kiichiro, Okamoto, Yukiharu, Ohshiro, Iwao, and Hirose, Tetsuhito. 1987. "Serum thymidine kinase activity of various cancer and HBV positive liver diseases." Japan.
@misc{etde_6414945,
title = {Serum thymidine kinase activity of various cancer and HBV positive liver diseases}
author = {Torizumi, Kazutami, Aibata, Hirofumi, Kiji, Shigeyuki, Ohta, Kiichiro, Okamoto, Yukiharu, Ohshiro, Iwao, and Hirose, Tetsuhito}
abstractNote = {Clinical utility of determination of serum deoxythymidine kinase (TK) activity is described. It is well known that elevated TK level is observed in leukemia and other malignant diseases, or some viral infectious diseases. The TK activity was assayed on normal subjects, hepatitis B virus (HBV) positive liver diseases and various cancer by a newly developed high sensitive method, radioenzyme assay (REA) utilizing /sup 125/I-iododeoxyuridine as the substrate. Measurement of TK activity by the REA is revealed to be useful for ''the marker of DNA metabolism anomaly'' in leukemia, etc.}
journal = {Radioisotopes (Tokyo); (Japan)}
volume = {36:3}
journal type = {AC}
place = {Japan}
year = {1987}
month = {Mar}
}