You need JavaScript to view this

Neuroradiology of the normal and pathological anatomy of the rat brain. Pt. 2. Microangiographic investigations of the vascularisation of transplanted malignant brain tumors

Abstract

70 BD-IX rats, in which chemically induced mixed gliomas have been transplanted intracerebrally, were investigated by microangiography. The pattern and the degree of tumor vascularisation of all animals was correlated with the histological findings. Dependent on the type of the tumor different localisations of tumor growth could be found: G XII-gliomas preferred the juxta-ventricular region and subarachnoid space whereas GL 2.2-gliomas mainly grew as solid intracerebral space occupying lesions. Microangiograms of all tumor stages from the 14th to 42nd day after transplantation revealed a typical vascular pattern consisting of lacunar glomerulose and netlike vessels. Further, necrosis, bleedings into the tumor, and irregularities of the capillary network could be demonstrated. The volume, age and vascularisation of the tumors are correlated and the results are discussed with regard to the principles of tumor growth and malignancy.
Publication Date:
Nov 01, 1980
Product Type:
Journal Article
Reference Number:
EDB-81-076556
Resource Relation:
Journal Name: Fortschr. Geb. Roentgenstr. Nuklearmed.; (Germany, Federal Republic of); Journal Volume: 133:5
Subject:
59 BASIC BIOLOGICAL SCIENCES; BRAIN; X-RAY RADIOGRAPHY; NEOPLASMS; BLOOD VESSELS; PATHOLOGICAL CHANGES; ANATOMY; PATHOLOGY; RATS; ANIMALS; BODY; CARDIOVASCULAR SYSTEM; CENTRAL NERVOUS SYSTEM; DISEASES; INDUSTRIAL RADIOGRAPHY; MAMMALS; NERVOUS SYSTEM; ORGANS; RODENTS; VERTEBRATES; 550901* - Pathology- Tracer Techniques
OSTI ID:
6409675
Country of Origin:
Germany
Language:
German
Other Identifying Numbers:
Journal ID: CODEN: FGRNA
Submitting Site:
DE
Size:
Pages: 514-520
Announcement Date:
Jun 01, 1981

Citation Formats

Schumacher, M, Weisser, G, Voigt, K, and Mennel, H D. Neuroradiology of the normal and pathological anatomy of the rat brain. Pt. 2. Microangiographic investigations of the vascularisation of transplanted malignant brain tumors. Germany: N. p., 1980. Web.
Schumacher, M, Weisser, G, Voigt, K, & Mennel, H D. Neuroradiology of the normal and pathological anatomy of the rat brain. Pt. 2. Microangiographic investigations of the vascularisation of transplanted malignant brain tumors. Germany.
Schumacher, M, Weisser, G, Voigt, K, and Mennel, H D. 1980. "Neuroradiology of the normal and pathological anatomy of the rat brain. Pt. 2. Microangiographic investigations of the vascularisation of transplanted malignant brain tumors." Germany.
@misc{etde_6409675,
title = {Neuroradiology of the normal and pathological anatomy of the rat brain. Pt. 2. Microangiographic investigations of the vascularisation of transplanted malignant brain tumors}
author = {Schumacher, M, Weisser, G, Voigt, K, and Mennel, H D}
abstractNote = {70 BD-IX rats, in which chemically induced mixed gliomas have been transplanted intracerebrally, were investigated by microangiography. The pattern and the degree of tumor vascularisation of all animals was correlated with the histological findings. Dependent on the type of the tumor different localisations of tumor growth could be found: G XII-gliomas preferred the juxta-ventricular region and subarachnoid space whereas GL 2.2-gliomas mainly grew as solid intracerebral space occupying lesions. Microangiograms of all tumor stages from the 14th to 42nd day after transplantation revealed a typical vascular pattern consisting of lacunar glomerulose and netlike vessels. Further, necrosis, bleedings into the tumor, and irregularities of the capillary network could be demonstrated. The volume, age and vascularisation of the tumors are correlated and the results are discussed with regard to the principles of tumor growth and malignancy.}
journal = []
volume = {133:5}
journal type = {AC}
place = {Germany}
year = {1980}
month = {Nov}
}