Abstract
When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays
Citation Formats
Ganatra, R D.
Future of nuclear medicine.
IAEA: N. p.,
1992.
Web.
Ganatra, R D.
Future of nuclear medicine.
IAEA.
Ganatra, R D.
1992.
"Future of nuclear medicine."
IAEA.
@misc{etde_640621,
title = {Future of nuclear medicine}
author = {Ganatra, R D}
abstractNote = {When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays}
place = {IAEA}
year = {1992}
month = {Dec}
}
title = {Future of nuclear medicine}
author = {Ganatra, R D}
abstractNote = {When it comes to setting up nuclear medicine in a developing country, there is a group of people, who feel that such high technology has no place in a developing country. RIA is likely to remain the method of choice for the research laboratory. The use of radioisotopic label has many advantages compared to the use of an enzyme marker. Generally, iodination is simpler than the preparation of an enzyme labelled substance, especially since there has been no agreement as to which enzyme is best for substances as small as steroids or a large as viruses. In addition, there may be some change in the configuration of the enzyme or the substance to be labelled during the conjugation procedure. Monoclonal antibodies can provide virtually unlimited amounts of homogenous antibodies against a specific antigenic site. The heterogeneous antibodies are more likely to provide more sensitive assays than the monoclonal antibodies, although assays employing the latter are likely to be more specific. The optimal choice of the antiserum may depend on whether sensitivity or specificity is required for the assays}
place = {IAEA}
year = {1992}
month = {Dec}
}