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Radiolabelled blood elements techniques and clinical applications

Abstract

Over the past few years, in nuclear medicine, the diagnostic applications of radiolabelled blood elements in general, and of radiolabelled white blood cells in particular, have become increasingly popular. This is primarily due to the introduction of lipid soluble {sup 111}In-oxine as an agent, which not only is an excellent and a reliable tracer for blood cells but also enables the investigators to study the in vivo cell kinetics and map the localization of labelled cells by external gamma scintigraphy. The tracer has the modest half life of 67 hours and decays with the emission of two gamma photons (173 and 247 keV) in high abundance. This technique has provided a powerful tool to study the in vivo cell kinetics in health and localize abnormal lesions in diseases which invoke intense focal cellular concentration 5 figs, 2 tabs
Authors:
Publication Date:
Dec 31, 1992
Product Type:
Technical Report
Report Number:
NMS-1
Reference Number:
SCA: 550601; PA: AIX-29:049622; EDB-98:095797; SN: 98002003658
Resource Relation:
Other Information: DN: 5 figs, 2 tabs; PBD: 1992; Related Information: Is Part Of Handbook of nuclear medicine practice in developing countries; PB: 728 p.
Subject:
55 BIOLOGY AND MEDICINE, BASIC STUDIES; BLOOD PLATELETS; BLOOD SERUM; CHROMIUM 51; DIAGNOSTIC TECHNIQUES; GAMMA CAMERAS; INDIUM 111; ISOTOPE APPLICATIONS; LABELLED COMPOUNDS; LABELLING; LEUKOCYTES; LYMPHOCYTES; PHAGOCYTES; PHAGOCYTOSIS; QUALITY CONTROL; TECHNETIUM 99
OSTI ID:
640610
Research Organizations:
International Atomic Energy Agency, Vienna (Austria). Nuclear Medicine Section
Country of Origin:
IAEA
Language:
English
Other Identifying Numbers:
Other: ON: DE98635463; TRN: XA9847624049622
Availability:
INIS; OSTI as DE98635463
Submitting Site:
INIS
Size:
pp. 497-516
Announcement Date:
Sep 18, 1998

Citation Formats

Thakur, M L. Radiolabelled blood elements techniques and clinical applications. IAEA: N. p., 1992. Web.
Thakur, M L. Radiolabelled blood elements techniques and clinical applications. IAEA.
Thakur, M L. 1992. "Radiolabelled blood elements techniques and clinical applications." IAEA.
@misc{etde_640610,
title = {Radiolabelled blood elements techniques and clinical applications}
author = {Thakur, M L}
abstractNote = {Over the past few years, in nuclear medicine, the diagnostic applications of radiolabelled blood elements in general, and of radiolabelled white blood cells in particular, have become increasingly popular. This is primarily due to the introduction of lipid soluble {sup 111}In-oxine as an agent, which not only is an excellent and a reliable tracer for blood cells but also enables the investigators to study the in vivo cell kinetics and map the localization of labelled cells by external gamma scintigraphy. The tracer has the modest half life of 67 hours and decays with the emission of two gamma photons (173 and 247 keV) in high abundance. This technique has provided a powerful tool to study the in vivo cell kinetics in health and localize abnormal lesions in diseases which invoke intense focal cellular concentration 5 figs, 2 tabs}
place = {IAEA}
year = {1992}
month = {Dec}
}