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Cerebrocerebellar relationships in normal subjects and patients with dementia of the Alzheimer type; A SPECT study

Abstract

The relationships bewteen blood flow in the cerebrum and the cerebellum was investigated in 21 normal subjects and 21 patients with dementia of the Alzheimer type (DAT). In normal subjects, only asymmetry in the frontal cortical blood flow was significantly correlated with asymmetry in the contralateral cerebellar blood flow. However, a significant correlation between asymmetry in the cerebral cortical blood flow in many areas and the blood flow in the contralateral cerebellum in DAT patients was observed. These results suggest the existence of a functional relationship between the cerebrum and the cerebellum in both normal and DAT groups, mediated by neuronal mechanisms through crossed fiber pathways. However, there are regional differences in the cerebrocerebellar relationship in normal resting and pathological states. (author).
Publication Date:
Feb 01, 1993
Product Type:
Journal Article
Reference Number:
JPN-93-005243; EDB-93-085979
Resource Relation:
Journal Name: Annals of Nuclear Medicine; (Japan); Journal Volume: 7:1
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; CEREBELLUM; SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY; CEREBRUM; BENZEDRINE; BLOOD FLOW; IODINE 123; MENTAL DISORDERS; AMINES; AUTONOMIC NERVOUS SYSTEM AGENTS; BETA DECAY RADIOISOTOPES; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DIAGNOSTIC TECHNIQUES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOISOTOPES; SYMPATHOMIMETICS; TOMOGRAPHY; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6387226
Country of Origin:
Japan
Language:
English
Other Identifying Numbers:
Journal ID: ISSN 0914-7187; CODEN: ANMEEX
Submitting Site:
JPN
Size:
Pages: 45-50
Announcement Date:
Jul 15, 1993

Citation Formats

Hanyu, Haruo, Arai, Hisayuki, Abe, Shin'e, Iwamoto, Toshihiko, Takasaki, Masaru, Katsunuma, Hideyo, Suzuki, Takanari, Abe, Kimihiko, and Amino, Saburo. Cerebrocerebellar relationships in normal subjects and patients with dementia of the Alzheimer type; A SPECT study. Japan: N. p., 1993. Web.
Hanyu, Haruo, Arai, Hisayuki, Abe, Shin'e, Iwamoto, Toshihiko, Takasaki, Masaru, Katsunuma, Hideyo, Suzuki, Takanari, Abe, Kimihiko, & Amino, Saburo. Cerebrocerebellar relationships in normal subjects and patients with dementia of the Alzheimer type; A SPECT study. Japan.
Hanyu, Haruo, Arai, Hisayuki, Abe, Shin'e, Iwamoto, Toshihiko, Takasaki, Masaru, Katsunuma, Hideyo, Suzuki, Takanari, Abe, Kimihiko, and Amino, Saburo. 1993. "Cerebrocerebellar relationships in normal subjects and patients with dementia of the Alzheimer type; A SPECT study." Japan.
@misc{etde_6387226,
title = {Cerebrocerebellar relationships in normal subjects and patients with dementia of the Alzheimer type; A SPECT study}
author = {Hanyu, Haruo, Arai, Hisayuki, Abe, Shin'e, Iwamoto, Toshihiko, Takasaki, Masaru, Katsunuma, Hideyo, Suzuki, Takanari, Abe, Kimihiko, and Amino, Saburo}
abstractNote = {The relationships bewteen blood flow in the cerebrum and the cerebellum was investigated in 21 normal subjects and 21 patients with dementia of the Alzheimer type (DAT). In normal subjects, only asymmetry in the frontal cortical blood flow was significantly correlated with asymmetry in the contralateral cerebellar blood flow. However, a significant correlation between asymmetry in the cerebral cortical blood flow in many areas and the blood flow in the contralateral cerebellum in DAT patients was observed. These results suggest the existence of a functional relationship between the cerebrum and the cerebellum in both normal and DAT groups, mediated by neuronal mechanisms through crossed fiber pathways. However, there are regional differences in the cerebrocerebellar relationship in normal resting and pathological states. (author).}
journal = []
volume = {7:1}
journal type = {AC}
place = {Japan}
year = {1993}
month = {Feb}
}