Abstract
The nigrostriatal dopaminergic function and glucose metabolism were evaluated in 34 patients with various movement disorders by using positron emission tomography with [sup 18]F-Dopa and [sup 18]F-FDG respectively. The [sup 18]F-Dopa uptake in the striatum (the caudate head and the putamen) decreased in patients with Parkinson's disease but was relatively unaffected in the caudate. The cerebral glucose metabolism was normal in patients with Parkinson's disease. The [sup 18]F-Dopa uptake in the striatum also decreased in cases of atypical parkinsonism and in cases of progressive supranuclear palsy, but there was no difference in the uptake between the caudate and the putamen. The glucose metabolism decreased in the cerebral hemisphere including the striatum; this finding was also different from those of Parkinson's disease. A normal [sup 18]F-Dopa uptake in the striatum with a markedly decreased striatal glucose metabolism and a mildly decreased cortical glucose metabolism was observed in cases of Huntington's disease and Wilson's disease. The [sup 18]F-Dopa uptake in the striatum increased and the glucose metabolism was normal in cases of idiopathic dystonia. Various patterns of [sup 18]F-Dopa uptake and glucose metabolism were thus observed in the various movement disorders. These results suggest that the measurements of the [sup 18]F-Dopa uptake
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Otsuka, Makoto;
Ichiya, Yuichi;
Kuwabara, Yasuo;
Sasaki, Masayuki;
Fukumura, Toshimitsu;
Masuda, Kouji;
Shima, Fumio;
Kato, Motohiro
[1]
- Kyushu Univ., Fukuoka (Japan). Faculty of Medicine
Citation Formats
Otsuka, Makoto, Ichiya, Yuichi, Kuwabara, Yasuo, Sasaki, Masayuki, Fukumura, Toshimitsu, Masuda, Kouji, Shima, Fumio, and Kato, Motohiro.
The measurement of the nigrostriatal dopaminergic function and glucose metabolism in patients with movement disorders.
Japan: N. p.,
1992.
Web.
Otsuka, Makoto, Ichiya, Yuichi, Kuwabara, Yasuo, Sasaki, Masayuki, Fukumura, Toshimitsu, Masuda, Kouji, Shima, Fumio, & Kato, Motohiro.
The measurement of the nigrostriatal dopaminergic function and glucose metabolism in patients with movement disorders.
Japan.
Otsuka, Makoto, Ichiya, Yuichi, Kuwabara, Yasuo, Sasaki, Masayuki, Fukumura, Toshimitsu, Masuda, Kouji, Shima, Fumio, and Kato, Motohiro.
1992.
"The measurement of the nigrostriatal dopaminergic function and glucose metabolism in patients with movement disorders."
Japan.
@misc{etde_6387092,
title = {The measurement of the nigrostriatal dopaminergic function and glucose metabolism in patients with movement disorders}
author = {Otsuka, Makoto, Ichiya, Yuichi, Kuwabara, Yasuo, Sasaki, Masayuki, Fukumura, Toshimitsu, Masuda, Kouji, Shima, Fumio, and Kato, Motohiro}
abstractNote = {The nigrostriatal dopaminergic function and glucose metabolism were evaluated in 34 patients with various movement disorders by using positron emission tomography with [sup 18]F-Dopa and [sup 18]F-FDG respectively. The [sup 18]F-Dopa uptake in the striatum (the caudate head and the putamen) decreased in patients with Parkinson's disease but was relatively unaffected in the caudate. The cerebral glucose metabolism was normal in patients with Parkinson's disease. The [sup 18]F-Dopa uptake in the striatum also decreased in cases of atypical parkinsonism and in cases of progressive supranuclear palsy, but there was no difference in the uptake between the caudate and the putamen. The glucose metabolism decreased in the cerebral hemisphere including the striatum; this finding was also different from those of Parkinson's disease. A normal [sup 18]F-Dopa uptake in the striatum with a markedly decreased striatal glucose metabolism and a mildly decreased cortical glucose metabolism was observed in cases of Huntington's disease and Wilson's disease. The [sup 18]F-Dopa uptake in the striatum increased and the glucose metabolism was normal in cases of idiopathic dystonia. Various patterns of [sup 18]F-Dopa uptake and glucose metabolism were thus observed in the various movement disorders. These results suggest that the measurements of the [sup 18]F-Dopa uptake and the cerebral glucose metabolism would be useful for the evaluation of the striatal function in various movement disorders. (author).}
journal = []
volume = {14:6}
journal type = {AC}
place = {Japan}
year = {1992}
month = {Dec}
}
title = {The measurement of the nigrostriatal dopaminergic function and glucose metabolism in patients with movement disorders}
author = {Otsuka, Makoto, Ichiya, Yuichi, Kuwabara, Yasuo, Sasaki, Masayuki, Fukumura, Toshimitsu, Masuda, Kouji, Shima, Fumio, and Kato, Motohiro}
abstractNote = {The nigrostriatal dopaminergic function and glucose metabolism were evaluated in 34 patients with various movement disorders by using positron emission tomography with [sup 18]F-Dopa and [sup 18]F-FDG respectively. The [sup 18]F-Dopa uptake in the striatum (the caudate head and the putamen) decreased in patients with Parkinson's disease but was relatively unaffected in the caudate. The cerebral glucose metabolism was normal in patients with Parkinson's disease. The [sup 18]F-Dopa uptake in the striatum also decreased in cases of atypical parkinsonism and in cases of progressive supranuclear palsy, but there was no difference in the uptake between the caudate and the putamen. The glucose metabolism decreased in the cerebral hemisphere including the striatum; this finding was also different from those of Parkinson's disease. A normal [sup 18]F-Dopa uptake in the striatum with a markedly decreased striatal glucose metabolism and a mildly decreased cortical glucose metabolism was observed in cases of Huntington's disease and Wilson's disease. The [sup 18]F-Dopa uptake in the striatum increased and the glucose metabolism was normal in cases of idiopathic dystonia. Various patterns of [sup 18]F-Dopa uptake and glucose metabolism were thus observed in the various movement disorders. These results suggest that the measurements of the [sup 18]F-Dopa uptake and the cerebral glucose metabolism would be useful for the evaluation of the striatal function in various movement disorders. (author).}
journal = []
volume = {14:6}
journal type = {AC}
place = {Japan}
year = {1992}
month = {Dec}
}