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Review of health risks in acrylonitrile industry

Journal Article:

Abstract

The Occupational Health Branch of the Ontario Ministry of Labour began a study in 1978 for the evaluation of health risks associated with acrylonitrile (AN) exposure. Detailed hygiene and medical investigations were conducted in fourteen plants for evaluating AN exposure in various industrial processes. For companies were also studied in relation to mixed chemical exposure representing acrylic fibres, nitrile rubber, ABS-resin, and acrylic emulsions production. The possible interaction between AN and other coexisting chemical exposures was reviewed since dimethyl formamide, styrene, and butadiene have similar pharmacokinetics and possible synergistic effects. Exposure in acrylic fibre production may be synergistic and carcinogenic. Results of air monitoring indicated exposure levels to AN below 2 ppm (TWA) in most cases. Exposure to other co-existing chemicals was evaluated. Results of medical tests indicated no significant abnormalities in chest x-rays or liver function tests in currently exposed workers.
Publication Date:
May 01, 1984
Product Type:
Journal Article
Reference Number:
EDB-86-005778
Resource Relation:
Journal Name: G. Ital. Med. Lav.; (Italy); Journal Volume: 3-4
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; 54 ENVIRONMENTAL SCIENCES; ACRYLONITRILE; AIR POLLUTION MONITORING; HEALTH HAZARDS; OCCUPATIONAL EXPOSURE; CHEMICAL INDUSTRY; INDOOR AIR POLLUTION; LIVER; OCCUPATIONAL DISEASES; SYNERGISM; AIR POLLUTION; BODY; DIGESTIVE SYSTEM; GLANDS; HAZARDS; INDUSTRY; MONITORING; NITRILES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; POLLUTION; 560306* - Chemicals Metabolism & Toxicology- Man- (-1987); 500200 - Environment, Atmospheric- Chemicals Monitoring & Transport- (-1989)
OSTI ID:
6376849
Country of Origin:
Italy
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: GIMLD
Submitting Site:
HEDB
Size:
Pages: 87-93
Announcement Date:

Journal Article:

Citation Formats

Guirguis, S S, Cohen, M B, and Rajhans, G S. Review of health risks in acrylonitrile industry. Italy: N. p., 1984. Web.
Guirguis, S S, Cohen, M B, & Rajhans, G S. Review of health risks in acrylonitrile industry. Italy.
Guirguis, S S, Cohen, M B, and Rajhans, G S. 1984. "Review of health risks in acrylonitrile industry." Italy.
@misc{etde_6376849,
title = {Review of health risks in acrylonitrile industry}
author = {Guirguis, S S, Cohen, M B, and Rajhans, G S}
abstractNote = {The Occupational Health Branch of the Ontario Ministry of Labour began a study in 1978 for the evaluation of health risks associated with acrylonitrile (AN) exposure. Detailed hygiene and medical investigations were conducted in fourteen plants for evaluating AN exposure in various industrial processes. For companies were also studied in relation to mixed chemical exposure representing acrylic fibres, nitrile rubber, ABS-resin, and acrylic emulsions production. The possible interaction between AN and other coexisting chemical exposures was reviewed since dimethyl formamide, styrene, and butadiene have similar pharmacokinetics and possible synergistic effects. Exposure in acrylic fibre production may be synergistic and carcinogenic. Results of air monitoring indicated exposure levels to AN below 2 ppm (TWA) in most cases. Exposure to other co-existing chemicals was evaluated. Results of medical tests indicated no significant abnormalities in chest x-rays or liver function tests in currently exposed workers.}
journal = {G. Ital. Med. Lav.; (Italy)}
volume = {3-4}
journal type = {AC}
place = {Italy}
year = {1984}
month = {May}
}