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Serum gastrin level in pregnancy running a normal course

Abstract

The serum gastrin level (SGL) is studied in dynamics during each lunar month of pregnancy in order to accumulate data which may serve the purpose of a tentative standard for serum gastrin level in this peculiar physiologic condition. A group of 110 pregnant women with a normal development of pregnancy, as documented by the clinical and paraclinical examination, are covered by the study. Blood samples are taken before meal, and a radioimmunologic method is used for SGL assessment. The number of women analyzed and the mean age by lunar months are shown. The normal value established in nonpregnant women of the same age group is 28+-7 mg/ml, relative to which the average values during the first five i.m. do not show statistically significant differences. During the 6th l.m. SGL increases to 68.5 mg/ml, while after the 7th l.m. values are recorded exceeding 1aa mg/ml with a maximum observed in the 8th and 9th l.m. The mechanisms eventually involved in the occurrence of gastrinemia during the second half of pregnancy are discussed, e.g. 1/mechanical compression of the stomach by the progressively growing uterus, 2/decreased breakdown, inhibition and elimimation of the hormone by the kidneys, and 3/possible correlative dependence between changes in  More>>
Authors:
Milev, N; Todorov, G; Pumpalov, A; Ignatov, A [1] 
  1. Meditsinska Akademiya, Sofia (Bulgaria). Nauchen Inst. po Rentgenologiya i Radiobiologiya
Publication Date:
Jan 01, 1982
Product Type:
Journal Article
Reference Number:
AIX-14-742407; EDB-83-078909
Resource Relation:
Journal Name: Probl. Rentgenol. Radiobiol.; (Bulgaria); Journal Volume: 3
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; GASTRIN; RADIOIMMUNOASSAY; PREGNANCY; HOMEOSTASIS; BLOOD SERUM; TIME DEPENDENCE; WOMEN; ANIMALS; FEMALES; HORMONES; ISOTOPE APPLICATIONS; MAMMALS; MAN; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PEPTIDES; POLYPEPTIDES; PRIMATES; PROTEINS; RADIOASSAY; TRACER TECHNIQUES; VERTEBRATES; 550601* - Medicine- Unsealed Radionuclides in Diagnostics
OSTI ID:
6376009
Country of Origin:
Bulgaria
Language:
Bulgarian
Other Identifying Numbers:
Journal ID: CODEN: PRRAD
Submitting Site:
HEDB
Size:
Pages: 106-111
Announcement Date:
Mar 01, 1983

Citation Formats

Milev, N, Todorov, G, Pumpalov, A, and Ignatov, A. Serum gastrin level in pregnancy running a normal course. Bulgaria: N. p., 1982. Web.
Milev, N, Todorov, G, Pumpalov, A, & Ignatov, A. Serum gastrin level in pregnancy running a normal course. Bulgaria.
Milev, N, Todorov, G, Pumpalov, A, and Ignatov, A. 1982. "Serum gastrin level in pregnancy running a normal course." Bulgaria.
@misc{etde_6376009,
title = {Serum gastrin level in pregnancy running a normal course}
author = {Milev, N, Todorov, G, Pumpalov, A, and Ignatov, A}
abstractNote = {The serum gastrin level (SGL) is studied in dynamics during each lunar month of pregnancy in order to accumulate data which may serve the purpose of a tentative standard for serum gastrin level in this peculiar physiologic condition. A group of 110 pregnant women with a normal development of pregnancy, as documented by the clinical and paraclinical examination, are covered by the study. Blood samples are taken before meal, and a radioimmunologic method is used for SGL assessment. The number of women analyzed and the mean age by lunar months are shown. The normal value established in nonpregnant women of the same age group is 28+-7 mg/ml, relative to which the average values during the first five i.m. do not show statistically significant differences. During the 6th l.m. SGL increases to 68.5 mg/ml, while after the 7th l.m. values are recorded exceeding 1aa mg/ml with a maximum observed in the 8th and 9th l.m. The mechanisms eventually involved in the occurrence of gastrinemia during the second half of pregnancy are discussed, e.g. 1/mechanical compression of the stomach by the progressively growing uterus, 2/decreased breakdown, inhibition and elimimation of the hormone by the kidneys, and 3/possible correlative dependence between changes in SGL and changes in the level of hormones playing a predominant role in the hormonal status after the fifth month of pregnancy.}
journal = []
volume = {3}
journal type = {AC}
place = {Bulgaria}
year = {1982}
month = {Jan}
}