You need JavaScript to view this

Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study

Abstract

In response to an entorhinal lesion, the commissural and associational afferents to the dentate gyrus have been shown to expand beyond their normal terminal zone into the area denervated by the entorhinal lesion. The present study has investigated the axonal transport of (/sup 3/H)-labeled proteins in the commissural and associational projections following an entorhinal lesion. Injections of (/sup 3/H)proline, (/sup 3/H)leucine or (/sup 3/H)fucose were given in the vicinity of the commissural and associational cells of origin before, immediately subsequent to, or at 5 to 15 days after the entorhinal lesion. The disposition of previously- or newly-synthesized proteins was examined in the commissural and associational terminal field at different times after an entorhinal lesion by light-microscopic autoradiography.
Authors:
Goldowitz, D; Cotman, C W [1] 
  1. California Univ., Irvine (USA)
Publication Date:
Dec 01, 1980
Product Type:
Journal Article
Reference Number:
AIX-12-610068; EDB-81-131908
Resource Relation:
Journal Name: Neuroscience; (United Kingdom); Journal Volume: 5:12
Subject:
59 BASIC BIOLOGICAL SCIENCES; BRAIN; AUTORADIOGRAPHY; NERVE CELLS; PROTEINS; BIOSYNTHESIS; TRANSLOCATION; HEXOSES; LABELLED COMPOUNDS; LEUCINE; PROLINE; RATS; TRITIUM; AMINES; AMINO ACIDS; ANIMAL CELLS; ANIMALS; AZOLES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CARBOXYLIC ACIDS; CENTRAL NERVOUS SYSTEM; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HYDROGEN ISOTOPES; ISOTOPES; LIGHT NUCLEI; MAMMALS; MONOSACCHARIDES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PYRROLES; PYRROLIDINES; RADIOISOTOPES; RODENTS; SACCHARIDES; SOMATIC CELLS; SYNTHESIS; VERTEBRATES; YEARS LIVING RADIOISOTOPES; 551001* - Physiological Systems- Tracer Techniques
OSTI ID:
6361216
Country of Origin:
United Kingdom
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: NRSCD
Submitting Site:
INIS
Size:
Pages: 2163-2174
Announcement Date:
Jul 01, 1981

Citation Formats

Goldowitz, D, and Cotman, C W. Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study. United Kingdom: N. p., 1980. Web. doi:10.1016/0306-4522(80)90133-5.
Goldowitz, D, & Cotman, C W. Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study. United Kingdom. https://doi.org/10.1016/0306-4522(80)90133-5
Goldowitz, D, and Cotman, C W. 1980. "Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study." United Kingdom. https://doi.org/10.1016/0306-4522(80)90133-5.
@misc{etde_6361216,
title = {Axonal transport and axon sprouting in the adult rat dentate gyrus: an autoradiographic study}
author = {Goldowitz, D, and Cotman, C W}
abstractNote = {In response to an entorhinal lesion, the commissural and associational afferents to the dentate gyrus have been shown to expand beyond their normal terminal zone into the area denervated by the entorhinal lesion. The present study has investigated the axonal transport of (/sup 3/H)-labeled proteins in the commissural and associational projections following an entorhinal lesion. Injections of (/sup 3/H)proline, (/sup 3/H)leucine or (/sup 3/H)fucose were given in the vicinity of the commissural and associational cells of origin before, immediately subsequent to, or at 5 to 15 days after the entorhinal lesion. The disposition of previously- or newly-synthesized proteins was examined in the commissural and associational terminal field at different times after an entorhinal lesion by light-microscopic autoradiography.}
doi = {10.1016/0306-4522(80)90133-5}
journal = []
volume = {5:12}
journal type = {AC}
place = {United Kingdom}
year = {1980}
month = {Dec}
}