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Quantitative regularities of development of endogenous infection in irradiated organism. (Survey of literature)

Abstract

A statistical analysis of data from the literature and the author's own experimental results are reviewed to show the functional relationships between the radiation dose and the development of endogenous infection in irradiated organisms. A direct linear dependence was found between the dose of radiation and the severity of endogenous infection at doses causing death from the ''bone marrow'' syndrome in acute radiation sickness. In case of death from the ''intestinal'' syndrome, an inverse linear dependence can be observed between the radiation dose and the culture yield of microbes from internal organs. In this case, the pathological effect on the organism is due to bacterial endotoxins formed during the disintegration of microbial cells in the organism. Endogenous infection and endotoxinaemia essentially aggravate the progress of acute radiation disease. The importance of endogenous infection for the death of the organism is minimized in irradiation at doses causing death ''under the ray''.
Authors:
Mal'tsev, V N [1] 
  1. Institut Biofiziki, Moscow (USSR)
Publication Date:
Jan 01, 1979
Product Type:
Journal Article
Reference Number:
AIX-12-595569; EDB-81-106492
Resource Relation:
Journal Name: J. Hyg., Epidemiol., Microbiol., Immunol.; (Czechoslovakia); Journal Volume: 23:2
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; INFECTIVITY; BIOLOGICAL RADIATION EFFECTS; RADIATION SYNDROME; DOSE-RESPONSE RELATIONSHIPS; ACUTE IRRADIATION; BONE MARROW; ENDOTOXINS; INTESTINES; LABORATORY ANIMALS; LETHAL IRRADIATION; MICROORGANISMS; REVIEWS; ACUTE EXPOSURE; ANIMAL TISSUES; ANTIGENS; BIOLOGICAL EFFECTS; BODY; DIGESTIVE SYSTEM; DOCUMENT TYPES; GASTROINTESTINAL TRACT; HEMATOPOIETIC SYSTEM; IRRADIATION; MATERIALS; ORGANS; RADIATION EFFECTS; TISSUES; TOXIC MATERIALS; TOXINS; 560131* - Radiation Effects on Microorganisms- Basic Studies- (-1987)
OSTI ID:
6340714
Country of Origin:
Serbia and Montenegro
Language:
English
Other Identifying Numbers:
Journal ID: CODEN: JHEMA
Submitting Site:
INIS
Size:
Pages: 121-128
Announcement Date:
Apr 01, 1981

Citation Formats

Mal'tsev, V N. Quantitative regularities of development of endogenous infection in irradiated organism. (Survey of literature). Serbia and Montenegro: N. p., 1979. Web.
Mal'tsev, V N. Quantitative regularities of development of endogenous infection in irradiated organism. (Survey of literature). Serbia and Montenegro.
Mal'tsev, V N. 1979. "Quantitative regularities of development of endogenous infection in irradiated organism. (Survey of literature)." Serbia and Montenegro.
@misc{etde_6340714,
title = {Quantitative regularities of development of endogenous infection in irradiated organism. (Survey of literature)}
author = {Mal'tsev, V N}
abstractNote = {A statistical analysis of data from the literature and the author's own experimental results are reviewed to show the functional relationships between the radiation dose and the development of endogenous infection in irradiated organisms. A direct linear dependence was found between the dose of radiation and the severity of endogenous infection at doses causing death from the ''bone marrow'' syndrome in acute radiation sickness. In case of death from the ''intestinal'' syndrome, an inverse linear dependence can be observed between the radiation dose and the culture yield of microbes from internal organs. In this case, the pathological effect on the organism is due to bacterial endotoxins formed during the disintegration of microbial cells in the organism. Endogenous infection and endotoxinaemia essentially aggravate the progress of acute radiation disease. The importance of endogenous infection for the death of the organism is minimized in irradiation at doses causing death ''under the ray''.}
journal = []
volume = {23:2}
journal type = {AC}
place = {Serbia and Montenegro}
year = {1979}
month = {Jan}
}