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Liver cirrhosis and primary carcinoma of the liver among atomic bomb survivors. Study of autopsy cases

Journal Article:

Abstract

Liver cirrhosis and primary carcinoma of the liver were investigated in 1699 autopsies of atomic bomb survivors carried out in Hiroshima from 1956 to 1980. Liver cirrhosis, hepatocellular carcinoma and intrahepatic biliary carcinoma were observed in 116, 111, and 17 cases respectively, the ratios of man to woman and were 2.3, 3.9, and 1.8 with a mean age of 56, 60, and 67 years respectively. There was no evidence that exposure to a-bomb increased the risk of these diseases significantly. About 90% of the hepatocellular carcinomas was combined with liver cirrhosis. Weight of liver and spleen, amount of ascites, hemorrhage from the digestive canals, esophageal varix, combination with other diseases, and histologic correlation with the activities of HBs antigen and ..cap alpha..-fetoprotein were discussed with the relation to the exposure.
Authors:
Hamada, T [1] 
  1. Hiroshima Atomic Bomb Hospital (Japan)
Publication Date:
Nov 01, 1980
Product Type:
Journal Article
Reference Number:
AIX-14-749812; EDB-83-097915
Resource Relation:
Journal Name: Nagasaki Igakkai Zasshi; (Japan); Journal Volume: 55
Subject:
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.; A-BOMB SURVIVORS; CARCINOMAS; LIVER CIRRHOSIS; AGE DEPENDENCE; ANNUAL VARIATIONS; AUTOPSY; DELAYED RADIATION EFFECTS; LIVER; METASTASES; PATHOLOGY; PATIENTS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DIGESTIVE SYSTEM DISEASES; DISEASES; GLANDS; HUMAN POPULATIONS; NEOPLASMS; ORGANS; POPULATIONS; RADIATION EFFECTS; VARIATIONS; 560121* - Radiation Effects on Cells- External Source- (-1987)
OSTI ID:
6340049
Country of Origin:
Japan
Language:
Japanese
Other Identifying Numbers:
Journal ID: CODEN: NAGZA
Submitting Site:
HEDB
Size:
Pages: 661-676
Announcement Date:

Journal Article:

Citation Formats

Hamada, T. Liver cirrhosis and primary carcinoma of the liver among atomic bomb survivors. Study of autopsy cases. Japan: N. p., 1980. Web.
Hamada, T. Liver cirrhosis and primary carcinoma of the liver among atomic bomb survivors. Study of autopsy cases. Japan.
Hamada, T. 1980. "Liver cirrhosis and primary carcinoma of the liver among atomic bomb survivors. Study of autopsy cases." Japan.
@misc{etde_6340049,
title = {Liver cirrhosis and primary carcinoma of the liver among atomic bomb survivors. Study of autopsy cases}
author = {Hamada, T}
abstractNote = {Liver cirrhosis and primary carcinoma of the liver were investigated in 1699 autopsies of atomic bomb survivors carried out in Hiroshima from 1956 to 1980. Liver cirrhosis, hepatocellular carcinoma and intrahepatic biliary carcinoma were observed in 116, 111, and 17 cases respectively, the ratios of man to woman and were 2.3, 3.9, and 1.8 with a mean age of 56, 60, and 67 years respectively. There was no evidence that exposure to a-bomb increased the risk of these diseases significantly. About 90% of the hepatocellular carcinomas was combined with liver cirrhosis. Weight of liver and spleen, amount of ascites, hemorrhage from the digestive canals, esophageal varix, combination with other diseases, and histologic correlation with the activities of HBs antigen and ..cap alpha..-fetoprotein were discussed with the relation to the exposure.}
journal = {Nagasaki Igakkai Zasshi; (Japan)}
volume = {55}
journal type = {AC}
place = {Japan}
year = {1980}
month = {Nov}
}